| Type | Description |
|---|---|
| Definition | vinculin a |
| Date | Results | Publications |
|---|---|---|
| 2020-05-30 13:16:00 | VCL recruits SSH1 and its effector, the actin depolymerizing factor cofilin (CFL), to regulate F-actin rearrangement and promote cardiomyocyte myofilament maturation | 31495694 |
| 2017-09-30 11:11:00 | Study show that zebrafish contain two homologous vinculin isoforms, of which the sequence of key functional domains is conserved with several higher vertebrate. Loss of both zygotic vcla and maternal contribution of vcla did not result in notable defects, while the additional loss of zygotic vclb is lethal only after embryonic stages. These data indicate that embryonic development in zebrafish can occur without vinculin. | 28767718 |
| Type | IDs |
|---|---|
| Synonymous | hm:zehn2160, im:6902790, vcl |
| Gene |
UniProtKB-ID:
B3DI32_DANRE,
F6NHA0_DANRE
UniprotKB:
B3DI32,
F6NHA0
UniParc:
UPI0001766148,
UPI0000F1F92D
EMBL:
CR788251,
CR762430,
BC162980,
CT025777
Ensembl:
ENSDARG00000044968
KO:
dre:552980
|
| Nucleutide sequences |
EMBL-CDS:
AAI62980.1
Ensembl_TRS:
ENSDART00000039828
|
| Protein sequencees |
Ensembl_PRO:
ENSDARP00000039827
RefSeq:
XP_021336251.1,
XP_005156899.1,
NP_001122153.1,
XP_005156897.1
|
| Others |
UniRef100:
UniRef100_B3DI32,
UniRef100_F6NHA0
UniRef90:
UniRef90_F6NHA0,
UniRef90_B3DI32
UniRef50:
UniRef50_P26234-2
UniGene:
Dr.78221
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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