| Type | Description |
|---|---|
| Definition | F-box and WD repeat domain containing 7 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-17 13:18:00 | Proteasomal degradation of the tumour suppressor FBW7 requires branched ubiquitylation by TRIP12. | 33824312 |
| 2021-04-17 13:11:00 | RASA1 inhibits the progression of renal cell carcinoma by decreasing the expression of miR-223-3p and promoting the expression of FBXW7. | 32588875 |
| 2021-04-13 10:12:00 | Decreased expression of FBXW7 by ERK1/2 activation in drug-resistant cancer cells confers transcriptional activation of MDR1 by suppression of ubiquitin degradation of HSF1. | 32457290 |
| 2021-04-03 13:31:00 | FBXW7 inhibited cell proliferation and invasion regulated by miR-27a through PI3K/AKT signaling pathway and epithelial-to-mesenchymal transition in oral squamous cell carcinoma. | 32329846 |
| 2021-04-03 13:30:00 | STYX/FBXW7 axis participates in the development of endometrial cancer cell via Notch-mTOR signaling pathway. | 32239181 |
| Type | IDs |
|---|---|
| Synonymous | AGO, CDC4, FBW6, FBW7, FBX30, FBXO30, FBXW6, SEL-10, SEL10, hAgo, hCdc4 |
| Gene |
UniProtKB-ID:
FBXW7_HUMAN,
G0Z2K0_HUMAN,
S4R3U4_HUMAN
UniprotKB:
Q969H0,
G0Z2K0,
S4R3U4
UniParc:
UPI0000035D56,
UPI0000035D51,
UPI000007007E,
UPI000219F7CF,
UPI0000D494FE
EMBL:
HQ873864,
AF411971,
HQ873866,
HQ873869,
AY049984,
AC080078,
AF411972,
HQ873868,
BC117246,
AF383178,
AC023424,
AY033553,
CR749305,
BC037320,
AK001933,
HQ873867,
BC143944,
AY008274,
HQ873865,
HQ873870,
BC117244
Ensembl:
ENSG00000109670
KO:
hsa:55294
|
| Nucleutide sequences |
EMBL-CDS:
AAI43945.1,
CAH18160.1,
AAG16640.1,
AAL06290.1,
AAK60269.1,
AAK57547.1,
AAI17247.1,
AAL07271.1,
BAA91986.1,
AAI17245.1,
AAH37320.1,
AAL06291.1,
AEK48275.1,
AEK48271.1,
AEK48274.1,
AEK48270.1,
AEK48273.1,
AEK48276.1,
AEK48272.1
Ensembl_TRS:
ENST00000393956,
ENST00000296555,
ENST00000281708,
ENST00000603841,
ENST00000603548,
ENST00000643834,
ENST00000642901,
ENST00000647166,
ENST00000604872
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000377528,
ENSP00000474725,
ENSP00000296555,
ENSP00000281708,
ENSP00000474971,
ENSP00000495905,
ENSP00000495702,
ENSP00000495753,
ENSP00000474751
RefSeq:
XP_011530388.1,
XP_011530386.1,
NP_001013433.1,
NP_001243998.1,
XP_024309891.1,
XP_011530387.1,
NP_361014.1,
XP_024309890.1,
XP_024309894.1,
XP_024309893.1,
XP_011530389.1,
XP_011530390.1,
XP_024309889.1,
NP_060785.2,
XP_024309892.1,
NP_001336727.1
|
| Others |
UniRef100:
UniRef100_Q969H0,
UniRef100_S4R3U4,
UniRef100_G0Z2K0
UniRef90:
UniRef90_S4R3U4,
UniRef90_Q969H0,
UniRef90_F6Q3K4
UniRef50:
UniRef50_Q969H0,
UniRef50_S4R3U4
UniGene:
Hs.561245,
Hs.717081
CCDS:
CCDS3778.1,
CCDS34078.1,
CCDS3777.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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