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55288 RHOT1

55288

RHOT1

ras homolog family member T1

protein-coding

Homo sapiens

基因描述

Type Description
Definition ras homolog family member T1

研究结论

Date Results Publications
2021-02-27 13:47:00 Miro: A molecular switch at the center of mitochondrial regulation. 32056317
2020-08-15 18:47:00 The ROTH1 is a genetic risk factor for Parkinson's disease, further implicating Miro1 in calcium homeostasis and mitochondrial quality control. 31303019
2020-04-04 11:15:00 circRHOT1 inhibits HCC development and progression via recruiting TIP60 to initiate NR2F6 expression, indicating that circRHOT1 and NR2F6 may be potential biomarkers for HCC prognosis. 31324186
2019-12-28 11:49:00 Results find that Miro1 is not only a substrate for PINK1/ Parkin-dependent degradation but might also function as a calcium-dependent docking site and safety switch for Parkin recruitment in mitochondria. 30504269
2019-12-07 11:28:00 Miro1 binds directly to a C-terminal fragment of the Myo19 tail region and that Miro1/2 recruit the Myo19 tail. 30111583

名称对应

Type IDs
Synonymous ARHT1, MIRO-1, MIRO1
Gene
UniProtKB-ID: MIRO1_HUMAN, H7BXZ6_HUMAN
UniprotKB: Q8IXI2, H7BXZ6
UniParc: UPI000041E9F7, UPI000020164E, UPI0000EE75E2, UPI0000037C11, UPI000040B3DA, UPI000020165E, UPI000020165D, UPI0000074394
EMBL: AC116407, AK001902, AY094972, AC026620, AJ517412, CH471147, BC060781, AK294407, AJ496730, AK022695, BC068463, BC015698, AL136929, BC041114, BC051818, BC125104, BC125105
Ensembl: ENSG00000126858
KO: hsa:55288
Nucleutide sequences
EMBL-CDS: AAI25105.1, AAH51818.1, BAG57659.1, AAH15698.1, AAM15734.1, CAD56956.1, AAH41114.1, BAB14185.1, CAD43139.1, AAH60781.2, BAA91969.1, CAB66863.1, AAI25106.1, AAH68463.1, EAW80251.1
Gene_ORFName: hCG_1991479
Ensembl_TRS: ENST00000581094, ENST00000545287, ENST00000581031, ENST00000333942, ENST00000394692, ENST00000358365, ENST00000354266
Protein sequencees
Ensembl_PRO: ENSP00000351132, ENSP00000334724, ENSP00000464094, ENSP00000378184, ENSP00000462669, ENSP00000439737, ENSP00000346215
RefSeq: XP_011523271.1, NP_001275684.1, XP_016880312.1, XP_016880308.1, XP_016880313.1, XP_024306595.1, NP_001028738.1, NP_060777.3, NP_001275687.1, XP_011523278.2, XP_016880309.1, NP_001028740.1, XP_011523273.2, XP_016880314.1, NP_001275683.1, XP_011523275.2, XP_016880311.1, XP_011523277.1, XP_016880310.1, NP_001028739.2
Others
UniRef100: UniRef100_Q8IXI2
UniRef90: UniRef90_Q8IXI2
UniRef50: UniRef50_Q8IXI2
UniGene: Hs.655325
CCDS: CCDS74030.1, CCDS32612.1, CCDS32610.1, CCDS32611.1

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