| Type | Description |
|---|---|
| Definition | ubiquitin conjugating enzyme E2 W |
| Date | Results | Publications |
|---|---|---|
| 2020-07-04 12:25:00 | we show in vitro that UBE2W can modify the N-terminus of both a-synuclein and a tau tetra-repeat domain with a single ubiquitin. We demonstrate that an engineered N-terminal ubiquitin modification changes the aggregation process of both proteins, resulting in the formation of structurally distinct aggregates | 31518613 |
| 2018-04-07 12:09:00 | Thus, although Rnf4 and Ube2w functionally interact in vitro, these genetic experiments indicate that in response to DNA damage Ube2w and Rnf4 function in distinct pathways. | 27185577 |
| 2015-10-31 10:36:00 | TRIM5alpha requires Ube2W to anchor Lys63-linked ubiquitin chains and restrict reverse transcription. | 26101372 |
| 2015-02-28 12:52:00 | We show the ubequitin-conjugating enzyme (E2) Ube2w uses a unique mechanism to facilitate the specific ubiquitination of the alpha-amino group | 25436519 |
| 2013-09-14 11:34:00 | Ube2w has novel enzymatic properties that direct ubiquitination of the N terminus of substrates | 23696636 |
| Type | IDs |
|---|---|
| Synonymous | UBC-16, UBC16 |
| Gene |
UniProtKB-ID:
UBE2W_HUMAN,
X6REH9_HUMAN,
Q96FI0_HUMAN
UniprotKB:
Q96B02,
X6REH9,
Q96FI0
UniParc:
UPI000004C55E,
UPI00027B2CEB,
UPI0000037726,
UPI0000EE3F3B,
UPI000006DBBC
EMBL:
CH471068,
BC010900,
CR457275,
AC022826,
AK295792,
AK024050,
AC022868,
AK001873,
AK021735,
AY948289,
BC016326
Ensembl:
ENSG00000104343
KO:
hsa:55284
|
| Nucleutide sequences |
EMBL-CDS:
EAW87011.1,
BAB14800.1,
BAG58613.1,
EAW87009.1,
BAB13883.1,
AAY24555.1,
BAA91954.1,
CAG33556.1,
AAH16326.1,
AAH10900.1
Ensembl_TRS:
ENST00000651945,
ENST00000517608,
ENST00000602593,
ENST00000650817,
ENST00000419880
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000428813,
ENSP00000499153,
ENSP00000473561,
ENSP00000498255,
ENSP00000397453
RefSeq:
NP_001257944.2,
NP_060769.5,
NP_001001481.3
|
| Others |
UniRef100:
UniRef100_Q96B02,
UniRef100_X6REH9,
UniRef100_Q96FI0
UniRef90:
UniRef90_A0A2I3GWU8,
UniRef90_Q96FI0,
UniRef90_Q96B02
UniRef50:
UniRef50_Q96B02,
UniRef50_Q96FI0,
UniRef50_A0A2I3GWU8
UniGene:
Hs.128841
CCDS:
CCDS47874.2,
CCDS47875.2
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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