| Type | Description |
|---|---|
| Definition | PHD finger protein 10 |
| Date | Results | Publications |
|---|---|---|
| 2019-05-04 10:14:00 | PHF10 expression in cells of different lines is activated by the c-MYC oncogene. Since PHF10 stimulates cell proliferation, its c-MYC-dependent activation in cancer cells should lead to an increase in their proliferation rate. | 31012017 |
| 2019-01-26 12:40:00 | Data show that PHF10 subunit of the PBAF signature module is the most unstable PBAF subunit, and demonstrate an important role of beta-TrCP ubiquitin ligase in regulation of PHF10 level and PBAF in general. Also, PHF10 isoforms contained two non-canonical beta-TrCP degrons and are degraded by beta-TrCP in a phospho-dependent manner. | 28717195 |
| 2017-02-04 12:44:00 | We studied the expression of S100A4 and the total PHF10 protein in some human cancer cell lines. We have found that, in the cell lines studied, the PHF10 expression is correlated with the S100A4 expression. | 27193724 |
| 2016-07-02 11:46:00 | Phosphorylation of PHF10 isoforms occurs while they are incorporated as a subunit of the PBAF complex, and therefore phosphorylation of PHF10 isoforms may play an essential role in regulation of PBAF complex's function and mechanism of action. | 27239853 |
| 2015-01-24 10:11:00 | The study demonstrates the existence of functionally different PBAF complexes in mammalian cell. It also provides an insight into the molecular structure and role of human PHF10/BAF45a and characterizes it as an essential PBAF subunit. | 24763304 |
| Type | IDs |
|---|---|
| Synonymous | BAF45A, XAP135 |
| Gene |
UniProtKB-ID:
PHF10_HUMAN
UniprotKB:
Q8WUB8
UniParc:
UPI0000EE1F6E,
UPI00017994F6,
UPI0001D1476E
EMBL:
AF338735,
AL513547,
BC110323,
AK001837,
BC020954,
AK222612,
CR457273
Ensembl:
ENSG00000130024
KO:
hsa:55274
|
| Nucleutide sequences |
EMBL-CDS:
CAG33554.1,
BAD96332.1,
AAI10324.1,
AAK27451.1,
BAA91934.1,
AAH20954.1
Ensembl_TRS:
ENST00000339209,
ENST00000621772,
ENST00000366780
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000341805,
ENSP00000355743,
ENSP00000484117
RefSeq:
NP_579866.2,
NP_060758.2
|
| Others |
UniRef100:
UniRef100_Q8WUB8
UniRef90:
UniRef90_Q8WUB8
UniRef50:
UniRef50_Q9D8M7
UniGene:
Hs.435933
CCDS:
CCDS5308.2,
CCDS5309.2
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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