| Type | Description |
|---|---|
| Definition | paraspeckle component 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-06 13:33:00 | PSPC1 Potentiates IGF1R Expression to Augment and Motility. | 32570949 |
| 2021-01-02 12:52:00 | Paraspeckle components NONO and PSPC1 are not mislocalized from motor neuron nuclei in sporadic ALS. | 32844195 |
| 2020-04-04 10:07:00 | PSPC1, a nuclear substrate of PTK6, sequesters PTK6 in the nucleus and loses its metastasis driving capability in hepatocellular carcinoma. Conversely, PSPC1 upregulation or PSPC1-Y523F mutation promotes epithelial-mesenchymal transition, stemness, and metastasis via cytoplasmic translocation of active PTK6 and nuclear translocation of beta-catenin, which interacts with PSPC1 to augment Wnt3a autocrine signaling. | 31844057 |
| 2019-10-05 11:30:00 | This study determined that Hepatitis Delta Virus replication induces the delocalization of PSP1 to cytoplasmic foci containing PABP and increases NEAT1 level causing an enlargement of NEAT1 foci. | 29662142 |
| 2019-05-11 13:06:00 | PSPC1 and TET2 contribute to ERVL and ERVL-associated gene regulation by both transcriptional repression via histone deacetylases and post-transcriptional destabilization of RNAs through 5hmC modification. | 29483655 |
| Type | IDs |
|---|---|
| Synonymous | PSP1 |
| Gene |
UniProtKB-ID:
PSPC1_HUMAN
UniprotKB:
Q8WXF1
UniParc:
UPI000006F2BE,
UPI00000724FE
EMBL:
AF448795,
CH471075,
AF449627,
AK001817,
BC014184,
AL834505,
AL354808,
CR457272
Ensembl:
ENSG00000121390
KO:
hsa:55269
|
| Nucleutide sequences |
EMBL-CDS:
EAX08232.1,
AAL59601.1,
CAD39162.1,
AAH14184.2,
CAG33553.1,
BAA91924.1,
AAL59602.1
Ensembl_TRS:
ENST00000492741,
ENST00000338910,
ENST00000619300,
ENST00000471658
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000436038,
ENSP00000343966,
ENSP00000481916,
ENSP00000435921
RefSeq:
NP_001350589.1,
XP_011533440.1,
XP_011533444.1,
NP_001341838.1,
XP_011533439.1,
XP_011533443.1,
NP_001341837.1,
NP_001035879.1,
XP_011533441.1
|
| Others |
UniRef100:
UniRef100_Q8WXF1
UniRef90:
UniRef90_Q8WXF1
UniRef50:
UniRef50_Q15233
UniGene:
Hs.213198
CCDS:
CCDS86343.1,
CCDS41870.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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