PPP2R5B - protein phosphatase 2 regulatory subunit B'beta-BMKCloudï½ç¾è¿å®¢äº

例如："NBL1", "4681", "drought"

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5526 PPP2R5B

基因描述

Type	Description
Definition	protein phosphatase 2 regulatory subunit B'beta

研究结论

Date	Results	Publications
2017-05-27 10:49:00	knockdown of B56beta attenuates hemin-induced K562 erythroid differentiation.	27544028
2016-05-14 12:11:00	Mutations in the PP2A regulatory subunit B family genes PPP2R5B, PPP2R5C and PPP2R5D cause human overgrowth	25972378
2013-03-02 10:52:00	KLHL15 can interact with the PP2A/B'beta heterotrimer, it only degrades B'beta, thus promoting exchange with other regulatory subunits.	23135275
2010-01-21 00:00:00	PP2A-Bbeta promotes cell migration through the MAPK cascade.	15665512

名称对应

Type	IDs
Synonymous	B56B, B56beta, PR61B
Gene	UniProtKB-ID: 2A5B_HUMAN, A0A024R593_HUMAN UniprotKB: Q15173, A0A024R593 UniParc: UPI000002A2B4, UPI000000DAF4 EMBL: L42374, CH471076, Z69028, BC045619 Ensembl: ENSG00000068971 KO: hsa:5526
Nucleutide sequences	EMBL-CDS: CAA93152.1, AAH45619.1, AAC37602.1, EAW74325.1, EAW74324.1 Gene_ORFName: hCG_23377 Ensembl_TRS: ENST00000164133
Protein sequencees	Ensembl_PRO: ENSP00000164133 RefSeq: NP_006235.1, XP_011543436.1, XP_011543435.1, XP_011543434.1
Others	UniRef100: UniRef100_Q15173 UniRef90: UniRef90_Q15173 UniRef50: UniRef50_Q15173 UniGene: Hs.75199 CCDS: CCDS8085.1

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mRNA

Protein

UniprotKB

Description

Refseq

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Pubmed编号	文献信息	发表日期	相关基因
32296183	A reference map of the human binary protein interactome. Nature Katja Luck , Dae-Kyum Kim , Luke Lambourne , Kerstin Spirohn , Bridget E Begg , Wenting Bian , Ruth Brignall , Tiziana Cafarelli , Francisco J Campos-Laborie , Benoit Charloteaux , Dongsic Choi , Atina G CotÃ© , Meaghan Daley , Steven Deimling , Alice Desbuleux , AmÃ©lie Dricot , Marinella Gebbia , Madeleine F Hardy , Nishka Kishore , Jennifer J Knapp , IstvÃ¡n A KovÃ¡cs , Irma Lemmens , Miles W Mee , Joseph C Mellor , Carl Pollis , Carles Pons , Aaron D Richardson , Sadie Schlabach , Bridget Teeking , Anupama Yadav , Mariana Babor , Dawit Balcha , Omer Basha , Christian Bowman-Colin , Suet-Feung Chin , Soon Gang Choi , Claudia Colabella , Georges Coppin , Cassandra D'Amata , David De Ridder , Steffi De Rouck , Miquel Duran-Frigola , Hanane Ennajdaoui , Florian Goebels , Liana Goehring , Anjali Gopal , Ghazal Haddad , Elodie Hatchi , Mohamed Helmy , Yves Jacob , Yoseph Kassa , Serena Landini , Roujia Li , Natascha van Lieshout , Andrew MacWilliams , Dylan Markey , Joseph N Paulson , Sudharshan Rangarajan , John Rasla , Ashyad Rayhan , Thomas Rolland , Adriana San-Miguel , Yun Shen , Dayag Sheykhkarimli , Gloria M Sheynkman , Eyal Simonovsky , Murat TaÅan , Alexander Tejeda , Vincent Tropepe , Jean-Claude Twizere , Yang Wang , Robert J Weatheritt , Jochen Weile , Yu Xia , Xinping Yang , Esti Yeger-Lotem , Quan Zhong , Patrick Aloy , Gary D Bader , Javier De Las Rivas , Suzanne Gaudet , Tong Hao , Janusz Rak , Jan Tavernier , David E Hill , Marc Vidal , Frederick P Roth , Michael A Calderwood	2020-04-01	-
30595372	De Novo Mutations Affecting the Catalytic CÎ± Subunit of PP2A, PPP2CA, Cause Syndromic Intellectual Disability Resembling Other PP2A-Related Neurodevelopmental Disorders. Am J Hum Genet Sara Reynhout , Sandra Jansen , Dorien Haesen , Siska van Belle , Sonja A de Munnik , Ernie M H F Bongers , Jolanda H Schieving , Carlo Marcelis , Jeanne Amiel , MarlÃ¨ne Rio , Heather Mclaughlin , Roger Ladda , Susan Sell , Marjolein Kriek , Cacha M P C D Peeters-Scholte , Paulien A Terhal , Koen L van Gassen , Nienke Verbeek , Sonja Henry , Jessica Scott Schwoerer , Saleem Malik , Nicole Revencu , Carlos R Ferreira , Ellen Macnamara , Hilde M H Braakman , Elise Brimble , Maura R Z Ruzhnikov , Matias Wagner , Philip Harrer , Dagmar Wieczorek , Alma Kuechler , Barak Tziperman , Ortal Barel , Bert B A de Vries , Christopher T Gordon , Veerle Janssens , Lisenka E L M Vissers	2019-01-03	-
29987050	Estrogen-regulated feedback loop limits the efficacy of estrogen receptor-targeted breast cancer therapy. Proc. Natl. Acad. Sci. U.S.A. Tengfei Xiao , Wei Li , Xiaoqing Wang , Han Xu , Jixin Yang , Qiu Wu , Ying Huang , Joseph Geradts , Peng Jiang , Teng Fei , David Chi , Chongzhi Zang , Qi Liao , Jonathan Rennhack , Eran Andrechek , Nanlin Li , Simone Detre , Mitchell Dowsett , Rinath M Jeselsohn , X Shirley Liu , Myles Brown	2018-07-31	-
28514442	Architecture of the human interactome defines protein communities and disease networks. Nature Edward L Huttlin , Raphael J Bruckner , Joao A Paulo , Joe R Cannon , Lily Ting , Kurt Baltier , Greg Colby , Fana Gebreab , Melanie P Gygi , Hannah Parzen , John Szpyt , Stanley Tam , Gabriela Zarraga , Laura Pontano-Vaites , Sharan Swarup , Anne E White , Devin K Schweppe , Ramin Rad , Brian K Erickson , Robert A Obar , K G Guruharsha , Kejie Li , Spyros Artavanis-Tsakonas , Steven P Gygi , J Wade Harper	2017-05-25	-
28330616	Systematic Analysis of Human Protein Phosphatase Interactions and Dynamics. Cell Syst Leena Yadav , Fitsum Tamene , Helka GÃ¶Ã¶s , Audrey van Drogen , Riku Katainen , Ruedi Aebersold , Matthias Gstaiger , Markku Varjosalo	2017-04-26	-
27880917	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators. Cell Rep Nicole St-Denis , Gagan D Gupta , Zhen Yuan Lin , Beatriz Gonzalez-Badillo , Amanda O Veri , James D R Knight , Dushyandi Rajendran , Amber L Couzens , Ko W Currie , Johnny M Tkach , Sally W T Cheung , Laurence Pelletier , Anne-Claude Gingras	2016-11-22	-
27544028	Protein phosphatase 2A regulatory subunit B56Î² modulates erythroid differentiation. Biochem. Biophys. Res. Commun. Jianping Wu , Jun Wang , Xiansheng Zeng , Yueqiu Chen , Jun Xia , Shizhen Wang , Zan Huang , Weiqian Chen , Zhenya Shen	2016-09-23	-
27432908	Defining the Protein-Protein Interaction Network of the Human Protein Tyrosine Phosphatase Family. Mol Cell Proteomics Xu Li , Kim My Tran , Kathryn E Aziz , Alexey V Sorokin , Junjie Chen , Wenqi Wang	2016-09-01	-
25972378	Mutations in the PP2A regulatory subunit B family genes PPP2R5B, PPP2R5C and PPP2R5D cause human overgrowth. Hum. Mol. Genet. Chey Loveday , Katrina Tatton-Brown , Matthew Clarke , Isaac Westwood , Anthony Renwick , Emma Ramsay , Andrea Nemeth , Jennifer Campbell , Shelagh Joss , McKinlay Gardner , Anna Zachariou , Anna Elliott , Elise Ruark , Rob van Montfort , Childhood Overgrowth Collaboration , Nazneen Rahman	2015-09-01	-
26186194	The BioPlex Network: A Systematic Exploration of the Human Interactome. Cell Edward L Huttlin , Lily Ting , Raphael J Bruckner , Fana Gebreab , Melanie P Gygi , John Szpyt , Stanley Tam , Gabriela Zarraga , Greg Colby , Kurt Baltier , Rui Dong , Virginia Guarani , Laura Pontano Vaites , Alban Ordureau , Ramin Rad , Brian K Erickson , Martin WÃ¼hr , Joel Chick , Bo Zhai , Deepak Kolippakkam , Julian Mintseris , Robert A Obar , Tim Harris , Spyros Artavanis-Tsakonas , Mathew E Sowa , Pietro De Camilli , Joao A Paulo , J Wade Harper , Steven P Gygi	2015-07-16	-

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