| Type | Description |
|---|---|
| Definition | cancer susceptibility 1 |
| Date | Results | Publications |
|---|---|---|
| 2010-12-05 22:08:00 | Observational study of gene-disease association. (HuGE Navigator) | 20734064 |
| 2010-09-15 22:06:00 | Observational study, meta-analysis, and genome-wide association study of gene-disease association. (HuGE Navigator) | 20639392 |
| 2008-04-03 08:26:00 | Observational study of gene-disease association. (HuGE Navigator) | 18299280 |
| 2008-03-13 08:52:00 | Observational study of gene-disease association. (HuGE Navigator) | 16410263 |
| Type | IDs |
|---|---|
| Synonymous | LAS1, PPP1R54 |
| Gene |
UniProtKB-ID:
CASC1_HUMAN,
B4E376_HUMAN
UniprotKB:
Q6TDU7,
B4E376
UniParc:
UPI0000E004AF,
UPI00001FB79F,
UPI00017A8883,
UPI0000DBEEF2,
UPI000056D3E6
EMBL:
AK304602,
CH471094,
AK001783,
BC057795,
AC023510,
BC047415,
BC028415,
AC092794,
BC117281,
BC117283,
AY423543,
AK297998
Ensembl:
ENSG00000118307
KO:
hsa:55259
|
| Nucleutide sequences |
EMBL-CDS:
AAI17284.2,
AAQ93499.1,
AAI17282.2,
AAH47415.2,
BAA91908.1,
AAH57795.1,
AAH28415.1,
BAG60304.1,
EAW96509.1,
BAG65388.1
Ensembl_TRS:
ENST00000320267,
ENST00000545133,
ENST00000395990,
ENST00000354189
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000379313,
ENSP00000437373,
ENSP00000346126,
ENSP00000313141
RefSeq:
NP_001306906.1,
NP_001338996.2,
XP_024304799.1,
NP_001306907.2,
XP_011519029.1,
NP_001338991.1,
XP_006719164.1,
XP_011519028.1,
NP_001076441.1,
NP_001338992.2,
NP_001338994.2,
XP_005253465.1,
XP_016875049.1,
NP_001338990.2,
NP_001191030.2,
XP_005253463.1,
NP_060742.4,
XP_016875054.1,
XP_011519025.1,
NP_001338993.2,
NP_001076442.2,
NP_001338995.2,
NP_001338997.1,
NP_001191031.2
|
| Others |
UniRef100:
UniRef100_B4E376,
UniRef100_Q6TDU7
UniRef90:
UniRef90_Q6TDU7,
UniRef90_B4E376
UniRef50:
UniRef50_A0A2Y9RJV9,
UniRef50_Q6TDU7
UniGene:
Hs.407771
CCDS:
CCDS41762.1,
CCDS55810.1,
CCDS55811.1,
CCDS41763.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 32296183 |
A reference map of the human binary protein interactome. Nature Katja Luck , Dae-Kyum Kim , Luke Lambourne , Kerstin Spirohn , Bridget E Begg , Wenting Bian , Ruth Brignall , Tiziana Cafarelli , Francisco J Campos-Laborie , Benoit Charloteaux , Dongsic Choi , Atina G Coté , Meaghan Daley , Steven Deimling , Alice Desbuleux , Amélie Dricot , Marinella Gebbia , Madeleine F Hardy , Nishka Kishore , Jennifer J Knapp , István A Kovács , Irma Lemmens , Miles W Mee , Joseph C Mellor , Carl Pollis , Carles Pons , Aaron D Richardson , Sadie Schlabach , Bridget Teeking , Anupama Yadav , Mariana Babor , Dawit Balcha , Omer Basha , Christian Bowman-Colin , Suet-Feung Chin , Soon Gang Choi , Claudia Colabella , Georges Coppin , Cassandra D'Amata , David De Ridder , Steffi De Rouck , Miquel Duran-Frigola , Hanane Ennajdaoui , Florian Goebels , Liana Goehring , Anjali Gopal , Ghazal Haddad , Elodie Hatchi , Mohamed Helmy , Yves Jacob , Yoseph Kassa , Serena Landini , Roujia Li , Natascha van Lieshout , Andrew MacWilliams , Dylan Markey , Joseph N Paulson , Sudharshan Rangarajan , John Rasla , Ashyad Rayhan , Thomas Rolland , Adriana San-Miguel , Yun Shen , Dayag Sheykhkarimli , Gloria M Sheynkman , Eyal Simonovsky , Murat TaÅan , Alexander Tejeda , Vincent Tropepe , Jean-Claude Twizere , Yang Wang , Robert J Weatheritt , Jochen Weile , Yu Xia , Xinping Yang , Esti Yeger-Lotem , Quan Zhong , Patrick Aloy , Gary D Bader , Javier De Las Rivas , Suzanne Gaudet , Tong Hao , Janusz Rak , Jan Tavernier , David E Hill , Marc Vidal , Frederick P Roth , Michael A Calderwood |
2020-04-01 | - |
| 30021884 |
Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei. Mol Cell Proteomics Domenico Fasci , Hugo van Ingen , Richard A Scheltema , Albert J R Heck |
2018-10-01 | - |
| 28514442 |
Architecture of the human interactome defines protein communities and disease networks. Nature Edward L Huttlin , Raphael J Bruckner , Joao A Paulo , Joe R Cannon , Lily Ting , Kurt Baltier , Greg Colby , Fana Gebreab , Melanie P Gygi , Hannah Parzen , John Szpyt , Stanley Tam , Gabriela Zarraga , Laura Pontano-Vaites , Sharan Swarup , Anne E White , Devin K Schweppe , Ramin Rad , Brian K Erickson , Robert A Obar , K G Guruharsha , Kejie Li , Spyros Artavanis-Tsakonas , Steven P Gygi , J Wade Harper |
2017-05-25 | - |
| 22990118 |
Charting the landscape of tandem BRCT domain-mediated protein interactions. Sci Signal Nicholas T Woods , Rafael D Mesquita , Michael Sweet , Marcelo A Carvalho , Xueli Li , Yun Liu , Huey Nguyen , C Eric Thomas , Edwin S Iversen , Sylvia Marsillac , Rachel Karchin , John Koomen , Alvaro N A Monteiro |
2012-01-01 |
RANBP9,
DPP3,
G3BP1,
RBM5,
ALYREF,
CDK5,
DCAF7,
SRRM1,
CDK9,
AKAP8,
SF3A1,
NPM3,
ANAPC10,
RACK1,
CD2BP2,
MCRS1,
PPIH,
CAP1,
LRRC41,
UNC13B,
FBLN5,
RPP30,
NPC2,
SMC2,
PAICS,
MYL12A,
CCT6B,
CFL1,
MGEA5,
NUDC,
AHCYL1,
SRSF10,
VAMP5,
RUVBL2,
CPSF4,
SUGT1,
DBF4,
KDELR1,
EBNA1BP2,
CKAP4,
MAPRE2,
COPS5,
IMMT,
ILVBL,
KIF2C,
CPSF6,
DDX52,
SOX30,
WDR5,
HNRNPUL1,
KRR1,
HIBADH,
FGFR1OP,
KIF3A,
CLASRP,
ZWINT,
WDHD1,
STRAP,
WDR6,
DDX20,
XPOT,
COPE,
GPN1,
PHB2,
CBX3,
U2AF2,
EXOSC8,
DTX2,
LACTB,
OSBPL8,
CIRBP,
DIS3L,
AP3S1,
BTBD16,
COMTD1,
PDZD8,
AGAP4,
CLU,
ANAPC16,
CLTC,
LSM12,
ZNF428,
COL1A1,
COL1A2,
SPATA18,
SPATA4,
CREBBP,
ZNF280B,
AAMP,
DNHD1,
CSNK2A1,
CSNK2B,
CARMIL2,
CSRP2,
SLC25A10,
CSTB,
CTBP1,
CTBP2,
COMMD1
|
| 20734064 |
A large-scale candidate gene association study of age at menarche and age at natural menopause. Hum. Genet. Chunyan He , Peter Kraft , Daniel I Chasman , Julie E Buring , Constance Chen , Susan E Hankinson , Guillaume Paré , Stephen Chanock , Paul M Ridker , David J Hunter |
2010-11-01 |
PPIF,
GDF11,
FST,
LEFTY1,
SLC12A7,
CGA,
ADAMTS13,
SLC2A6,
CHRNA1,
CHRNA2,
CHRNA3,
CHRNA4,
CHRNA5,
CHRNA7,
CHRNB1,
CHRNB2,
CHRNB3,
CHRNB4,
CHRND,
CHRNE,
CHRNG,
CCR3,
NLRP5,
CNR1,
PROKR2,
ACVR1C,
COMT,
CRHR1,
CRHR2,
MAPK14,
EME1,
GDF7,
SLC2A12,
ADRB2,
CYP1A1,
CYP1A2,
CYP1B1,
CYP2A6,
CYP2B6,
GRK3,
CYP3A4,
CYP11A1,
CYP17A1,
CYP19A1,
DBH,
ACE,
CITED4,
DDC,
AKR1C2,
DIAPH2,
DRD1,
DRD2,
DRD3,
DRD5,
AGT,
ECT2,
EML1,
AKT1,
ESR1,
ESR2,
F2,
F5,
ALDH1B1,
FGFR1,
FMO1,
FMO3,
FMR1,
AFF2,
LEPROTL1,
FSHB,
FSHR,
ANKK1,
PCSK9,
GABRB2,
GALT,
FGFR1OP2,
GDF1,
GDF2,
MSTN,
GDF9,
GDF10,
AMH,
GH1,
GHR,
GHRH,
AMHR2,
GHRHR,
BMP10,
GNB3,
GNRH1,
GNRHR,
MCHR1,
NR3C1,
HBE1,
HIVEP1,
AIRE,
HSD3B1,
HSD3B2,
HSD17B1
|
| 20639392 |
Genome-wide association analysis identifies multiple loci related to resting heart rate. Hum Mol Genet Mark Eijgelsheim , Christopher Newton-Cheh , Nona Sotoodehnia , Paul I W de Bakker , Martina Müller , Alanna C Morrison , Albert V Smith , Aaron Isaacs , Serena Sanna , Marcus Dörr , Pau Navarro , Christian Fuchsberger , Ilja M Nolte , Eco J C de Geus , Karol Estrada , Shih-Jen Hwang , Joshua C Bis , Ina-Maria Rückert , Alvaro Alonso , Lenore J Launer , Jouke Jan Hottenga , Fernando Rivadeneira , Peter A Noseworthy , Kenneth M Rice , Siegfried Perz , Dan E Arking , Tim D Spector , Jan A Kors , Yurii S Aulchenko , Kirill V Tarasov , Georg Homuth , Sarah H Wild , Fabio Marroni , Christian Gieger , Carmilla M Licht , Ronald J Prineas , Albert Hofman , Jerome I Rotter , Andrew A Hicks , Florian Ernst , Samer S Najjar , Alan F Wright , Annette Peters , Ervin R Fox , Ben A Oostra , Heyo K Kroemer , David Couper , Henry Völzke , Harry Campbell , Thomas Meitinger , Manuela Uda , Jacqueline C M Witteman , Bruce M Psaty , H-Erich Wichmann , Tamara B Harris , Stefan Kääb , David S Siscovick , Yalda Jamshidi , André G Uitterlinden , Aaron R Folsom , Martin G Larson , James F Wilson , Brenda W Penninx , Harold Snieder , Peter P Pramstaller , Cornelia M van Duijn , Edward G Lakatta , Stephan B Felix , Vilmundur Gudnason , Arne Pfeufer , Susan R Heckbert , Bruno H Ch Stricker , Eric Boerwinkle , Christopher J O'Donnell |
2010-10-01 | - |
| 19389623 |
Docking motif-guided mapping of the interactome of protein phosphatase-1. Chem. Biol. Annick Hendrickx , Monique Beullens , Hugo Ceulemans , Tom Den Abt , Aleyde Van Eynde , Emilia Nicolaescu , Bart Lesage , Mathieu Bollen |
2009-04-24 |
FARP1,
MPHOSPH10,
CD2BP2,
CENPE,
KDM5B,
LMTK3,
ELFN2,
PPP1R27,
TMEM132D,
WDR81,
PPP1R21,
ZSWIM3,
PPP1R36,
SH3RF2,
SPRED1,
CNST,
DLG2,
DLG3,
PPP1R32,
PPP1R35,
RRP1B,
FKBP15,
RPGRIP1L,
RIMBP2,
ZBTB38,
TRPC4AP,
SACS,
PCDH11X,
GPR12,
PPP1R37,
TRIM42,
UBN1,
TMEM225,
ITPR3,
GRXCR1,
ELFN1,
MAP1B,
MCM7,
MKI67,
MYO1D,
ORC5,
VPS54,
ZFYVE1,
KCNK10,
HYDIN,
SYTL2,
CHCHD3,
PPP1CA,
GPATCH2,
CEP192,
CASC1,
CASC5,
ARFGEF3,
PHRF1,
CAMSAP3,
SLC7A14,
TSKS,
SH2D4A,
PCIF1,
RBM26,
CSMD1,
DDX31,
WNK1,
TSC2,
CSRNP3,
PREX2,
CSRNP2,
ELL,
CCDC8,
ZCCHC9,
CHCHD6,
NIFK,
SPOCD1,
PKMYT1,
TMEM132C,
KIAA0430,
DZIP3,
SFI1,
SPATA2,
PPP1R26,
PPP1CA
|
| 18299280 |
Carcinogenesis Takashi Kohno , Hideo Kunitoh , Kenji Suzuki , Seiichiro Yamamoto , Aya Kuchiba , Yoshihiro Matsuno , Noriko Yanagitani , Jun Yokota |
2008-05-01 |
KRAS,
LRMP,
CASC1
|
| 16410263 |
A V141L polymorphism of the human LRMP gene is associated with survival of lung cancer patients. Carcinogenesis Giacomo Manenti , Federica Galbiati , Angela Pettinicchio , Monica Spinola , Silvia Piconese , Vera Piera Leoni , Barbara Conti , Fernando Ravagnani , Matteo Incarbone , Ugo Pastorino , Tommaso A Dragani |
2006-07-01 |
LRMP,
CASC1
|
| 16344560 |
Genome Res. Kouichi Kimura , Ai Wakamatsu , Yutaka Suzuki , Toshio Ota , Tetsuo Nishikawa , Riu Yamashita , Jun-ichi Yamamoto , Mitsuo Sekine , Katsuki Tsuritani , Hiroyuki Wakaguri , Shizuko Ishii , Tomoyasu Sugiyama , Kaoru Saito , Yuko Isono , Ryotaro Irie , Norihiro Kushida , Takahiro Yoneyama , Rie Otsuka , Katsuhiro Kanda , Takahide Yokoi , Hiroshi Kondo , Masako Wagatsuma , Katsuji Murakawa , Shinichi Ishida , Tadashi Ishibashi , Asako Takahashi-Fujii , Tomoo Tanase , Keiichi Nagai , Hisashi Kikuchi , Kenta Nakai , Takao Isogai , Sumio Sugano |
2006-01-01 |
Nefm,
MED6,
CDH2,
PDZK1P1,
DDTL,
ABI1,
GNPDA1,
GTF2IP4,
ZSCAN30,
SRA1,
TMEM170B,
HOTAIR,
FAM86JP,
LOC100126784,
C8orf88,
LOC100128006,
RAB28P5,
MYHAS,
CDC42P3,
LOC100128979,
LOC100128993,
KTN1-AS1,
LOC100129083,
LOC100129204,
TOPORS-AS1,
LINC00484,
ZNF37BP,
FAM47E,
MRVI1-AS1,
ZNF737,
LOC100130075,
MAPT-IT1,
MIR124-2HG,
LINC00861,
LOC100130238,
LOC100130357,
PARD6G-AS1,
LOC100130547,
NFYC-AS1,
EFCAB10,
LOC100130798,
SBK3,
LOC100130849,
LOC100130872,
LOC100130880,
LOC100130987,
LOC100131047,
LINC01135,
CKMT2-AS1,
ZBTB20-AS1,
WDR86-AS1,
CCDC183-AS1,
SNAP25-AS1,
NEMP2,
ZNF503-AS2,
MIR181A1HG,
DBIL5P,
HDAC6,
MZF1-AS1,
ARMCX4,
LINC00271,
ZNF717,
LOC100132057,
LOC100132111,
CALML3-AS1,
NDUFA6-AS1,
FRG1HP,
FCGR1CP,
GXYLT1P3,
GOLGA8F,
DCAF13P3,
IPO5P1,
MSC-AS1,
SMIM9,
FAM66A,
CD24,
UXT-AS1,
JHDM1D-AS1,
UBE2Q2P2,
TEN1,
JMJD7,
PLA2G4B,
LINC00930,
PDCD6IP,
HECTD2-AS1,
ZFHX4-AS1,
FAR2P2,
LOC100233156,
PCED1B-AS1,
PIGK,
LOC100270746,
LOC100270804,
LINC00940,
ERVV-2,
MEF2B,
ZNRF2P2,
NFE2L3P2,
LINC00894,
BCDIN3D-AS1
|
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员