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55256 ADI1

55256

ADI1

acireductone dioxygenase 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition acireductone dioxygenase 1

研究结论

Date Results Publications
2020-12-05 13:00:00 Acireductone dioxygenase 1 (ADI1) is regulated by cellular iron by a mechanism involving the iron chaperone, PCBP1, with PCBP2 acting as a potential co-chaperone. 32480040
2019-10-26 11:48:00 Pancreatic tumor cell metastasis is restricted by MT1-MMP binding protein MTCBP-1. 30487181
2018-11-24 10:26:00 High ADI1 expression is associated with malignant glioma. 30066900
2017-06-10 10:21:00 The thermal stability of the HsARD isozymes is a function of the metal ion identity, with Ni2+-bound HsARD being the most stable followed by Co2+ and Fe2+, and Mn2+-bound HsARD being the least stable. 28062648
2016-12-17 11:55:00 In summary, clinical and cell-based experiments suggested that physical interaction between MT1-MMP and ADI1 led to suppression of hepatitis C virus infection. This inhibitory effect could be reversed by ADI1 overexpression. 26537061

名称对应

Type IDs
Synonymous APL1, ARD, Fe-ARD, HMFT1638, MTCBP1, Ni-ARD, SIPL, mtnD
Gene
UniProtKB-ID: MTND_HUMAN
UniprotKB: Q9BV57
UniParc: UPI00001C0E3C, UPI000006D8C6
EMBL: AB158319, AK001775, AB073609, AC114810, AK222467, AK127473, AF087863, BC001467, CH471053, AC142528, AF403478
Ensembl: ENSG00000182551
KO: hsa:55256
Nucleutide sequences
EMBL-CDS: EAX01064.1, EAX01065.1, BAC86996.1, AAH01467.1, BAA91901.1, AAP97173.1, BAD96187.1, AAY24022.1, AAX82038.1, BAD10866.1, AAL25800.1, BAD38646.1
Gene_ORFName: HMFT1638
Ensembl_TRS: ENST00000327435, ENST00000382093
Protein sequencees
Ensembl_PRO: ENSP00000333666, ENSP00000371525
RefSeq: NP_001293006.1, NP_060739.2
Others
UniRef100: UniRef100_Q9BV57
UniRef90: UniRef90_Q9BV57
UniRef50: UniRef50_Q9BV57
UniGene: Hs.502773
CCDS: CCDS1653.1, CCDS77380.1

全选

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