| Type | Description |
|---|---|
| Definition | WD repeat domain 41 |
| Date | Results | Publications |
|---|---|---|
| 2020-09-26 13:09:00 | Structure of the C9orf72 ARF GAP complex that is haploinsufficient in ALS and FTD. | 32848248 |
| 2020-08-01 12:06:00 | Our study not only illustrates the basis of C9ORF72-SMCR8-WDR41 complex assembly but also reveals the GAP activity of the C9ORF72-SMCR8 complex | 32303654 |
| 2019-04-27 11:35:00 | Study reveals an essential role for WDR41 in supporting the regulated binding of C9orf72 to lysosomes and solidifies the requirement for a larger C9orf72 containing protein complex in coordinating lysosomal responses to changes in amino acid availability. | 29995611 |
| 2017-10-28 13:20:00 | Study describes the identification of two binding partners for C9orf72: SMCR8 and WDR41 and demonstrated that C9orf72/SMCR8/WDR41 interacts with the FIP200/Ulk1/ATG13/ATG101 complex. | 27193190 |
| 2012-01-21 10:35:00 | The peak of association was found in and around two genes, WDR41 and PDE8B, involved in dopamine signaling and development. | 21502949 |
| Type | IDs |
|---|---|
| Synonymous | MSTP048 |
| Gene |
UniProtKB-ID:
WDR41_HUMAN,
A0A0S2Z5E0_HUMAN
UniprotKB:
Q9HAD4,
A0A0S2Z5E0
UniParc:
UPI00017A7B34,
UPI00000744EF
EMBL:
AK023977,
AF115511,
AL834138,
AC010234,
KU178690,
AK021855,
AC108173,
AK300058,
BC040241,
AK001766
Ensembl:
ENSG00000164253
KO:
hsa:55255
|
| Nucleutide sequences |
EMBL-CDS:
BAB13915.1,
CAD38853.2,
AAO06948.1,
BAG61867.1,
AAH40241.1,
BAA91895.1,
BAB14749.1,
ALQ34148.1
Gene_ORFName:
MSTP048
Ensembl_TRS:
ENST00000296679,
ENST00000507029
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000296679,
ENSP00000424287
RefSeq:
NP_060738.2,
XP_011541809.1,
XP_016865095.1,
XP_005248609.1,
XP_005248608.1,
XP_011541807.1
|
| Others |
UniRef100:
UniRef100_Q9HAD4
UniRef90:
UniRef90_Q9HAD4
UniRef50:
UniRef50_Q9HAD4
UniGene:
Hs.482573
CCDS:
CCDS4038.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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