| Type | Description |
|---|---|
| Definition | ASXL transcriptional regulator 2 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-13 10:14:00 | [The Relationship between ASXL2 and ZBTB7A Gene Mutations and Prognosis in Patients with Acute Myeloid Leukemia]. | 33812414 |
| 2020-02-22 12:11:00 | ASXL2 gene mutation may not be closely related with C-KIT gene mutation | 32027264 |
| 2019-12-07 10:40:00 | ASXL2 mutation was frequent in non-de novo AML1-ETO-negative AML. 6 ASXL2 mutated AML patients were studied in detail and all ASXL2-mutated de-novo AML was positive for AML1-ETO; however, other ASXL2-mutated AML belonged to non-de-novo AML and they all were negative for AML1-ETO in this study. | 31637484 |
| 2019-09-07 11:44:00 | after KIT and NRAS, ASXL2 is among the most frequently mutated genes in t(8;21)-positive acute myeloid leukemia (AML), occurring in almost 17% of the patients in the cohort; high incidence and the exclusivity of ASXL2 mutation in this AML subset implies its particular role as a potential co-operating event in leukemogenesis of t(8;21)-positive AML | 28090090 |
| 2019-01-26 10:44:00 | ASXL2 and ZBTB7A mutations were frequently identified in Japanese AML patients with t(8;21), but not in those with inv(16). Further analysis is required to clarify the detailed biological mechanism of AE9a regulation of the cohesin complex. | 30251205 |
| Type | IDs |
|---|---|
| Synonymous | ASXH2, SHAPNS |
| Gene |
UniProtKB-ID:
ASXL2_HUMAN
UniprotKB:
Q76L83
UniParc:
UPI00001DFBE8,
UPI0000246C78
EMBL:
AB051472,
CR933613,
AB084281,
AB084279,
AC010150,
BC042999,
AK001760
Ensembl:
ENSG00000143970
KO:
hsa:55252
|
| Nucleutide sequences |
EMBL-CDS:
AAY14841.1,
BAA91889.1,
AAH42999.1,
BAB21776.2,
BAD00088.1,
CAI45930.1,
BAD00086.1
Ensembl_TRS:
ENST00000404843,
ENST00000435504
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000383920,
ENSP00000391447
RefSeq:
NP_001356275.1,
NP_001356276.1,
NP_060733.4
|
| Others |
UniRef100:
UniRef100_Q76L83
UniRef90:
UniRef90_Q76L83
UniRef50:
UniRef50_Q76L83
UniGene:
Hs.119815
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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