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55240 STEAP3

55240

STEAP3

STEAP3 metalloreductase

protein-coding

Homo sapiens

基因描述

Type Description
Definition STEAP3 metalloreductase

研究结论

Date Results Publications
2020-08-01 10:40:00 This article is the first report of a role of Steap3 in mature RBCs; it defines a new mechanism of redox biology in RBCs with a substantial effect upon RBC function and provides a novel mechanistic determinant of genetic variation of RBC storage. 31350307
2020-06-13 10:25:00 this study identified oxidative stress-dependent upregulation of the iron-converting metalloreductase, STEAP3, as a key mediator of extracellular matrix production in wound healing 31176711
2018-11-10 11:59:00 In hepatocellular carcinoma (HCC), lower expression of the STEAP3 copper reductase and heavy Cu isotope enrichment have been reported for the tumor mass, relative to the surrounding tissue 28303916
2017-09-02 12:09:00 TSAP6 over expression is associated with poor survival in metastatic high-grade serous carcinoma. 27825812
2016-08-13 11:22:00 heterozygous STEAP3 mutations are relatively common in humans and that their deleterious effect in humans remains to be confirmed 26675350

名称对应

Type IDs
Synonymous AHMIO2, STMP3, TSAP6, dudlin-2, dudulin-2, pHyde
Gene
UniProtKB-ID: STEA3_HUMAN, A1P3F0_HUMAN, B8ZZX6_HUMAN
UniprotKB: Q658P3, A1P3F0, B8ZZX6
UniParc: UPI00014F7AFB, UPI000013D445, UPI00014F7AFA, UPI000000D8FA, UPI0000207E04
EMBL: AY082673, BX538047, AK291608, BC095421, AF238864, BC042150, AF423424, AF262322, AL833624, CH471103, AK001691, AY029585, AC016673, AC016736, AY214461
Ensembl: ENSG00000115107
KO: hsa:55240
Nucleutide sequences
EMBL-CDS: CAD97986.1, AAO38238.1, AAQ04065.1, AAX88963.1, BAA91839.1, AAM08128.1, AAY14872.1, AAM45136.1, BAF84297.1, CAH56204.1, AAL78206.1, AAH95421.2, AAH42150.1, EAW95209.1, AAK50538.1, EAW95210.1, EAW95212.1, EAW95211.1
Gene_ORFName: hCG_18273, hCG_18273
Ensembl_TRS: ENST00000393107, ENST00000393110, ENST00000393106, ENST00000409811
Protein sequencees
Ensembl_PRO: ENSP00000376819, ENSP00000376818, ENSP00000376822, ENSP00000386510
RefSeq: XP_006712678.1, NP_878919.2, XP_006712677.1, NP_060704.2, XP_011509705.1, NP_001008410.1, NP_619543.2
Others
UniRef100: UniRef100_Q658P3, UniRef100_B8ZZX6
UniRef90: UniRef90_Q658P3, UniRef90_Q658P3-4
UniRef50: UniRef50_Q658P3, UniRef50_Q658P3-4
UniGene: Hs.647822
CCDS: CCDS42738.1, CCDS2125.1

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