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55238 SLC38A7

55238

SLC38A7

solute carrier family 38 member 7

protein-coding

Homo sapiens

基因描述

Type Description
Definition solute carrier family 38 member 7

研究结论

Date Results Publications
2020-04-04 11:43:00 GWAS identified a novel gene encoding an anastrozole transporter, SLC38A7, as well as epistatic interaction between SNPs in that gene and SNPs near ALPPL2 that influenced both the expression of the transporter and anastrozole plasma concentrations 30648747
2018-04-28 10:16:00 Cell fractionation confirmed the lysosomal localization of SNAT7, and flux measurements confirmed its substrate selectivity and showed a strong activation by the lysosomal pH gradient. Interestingly, gene silencing or editing experiments revealed that SNAT7 is the primary permeation pathway for glutamine across the lysosomal membrane and it is required for growth of cancer cells in a low free-glutamine environment. 28416685

名称对应

Type IDs
Synonymous SNAT7
Gene
UniProtKB-ID: S38A7_HUMAN, H3BMC5_HUMAN
UniprotKB: Q9NVC3, H3BMC5
UniParc: UPI000004EC72, UPI0000D4BEFC, UPI00004095AB
EMBL: CH471092, CR457236, AK222932, AK022786, AC010287, BC001961, AK001677
Ensembl: ENSG00000103042
KO: hsa:55238
Nucleutide sequences
EMBL-CDS: BAA91830.1, BAD96652.1, BAB14244.1, EAW82985.1, AAH01961.1, CAG33517.1
Ensembl_TRS: ENST00000219320, ENST00000570101, ENST00000564100
Protein sequencees
Ensembl_PRO: ENSP00000454646, ENSP00000219320, ENSP00000454325
RefSeq: NP_001356539.1, XP_016878884.1, XP_016878888.1, NP_001295313.1, NP_001356538.1, NP_001356537.1, NP_001356540.1, NP_060701.1, XP_016878885.1, XP_016878887.1
Others
UniRef100: UniRef100_Q9NVC3, UniRef100_H3BMC5
UniRef90: UniRef90_Q9NVC3, UniRef90_A0A2K6N0E2
UniRef50: UniRef50_Q9NVC3, UniRef50_A0A2K6N0E2
UniGene: Hs.10499
CCDS: CCDS10800.1

全选

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