| Type | Description |
|---|---|
| Definition | ubiquitin like modifier activating enzyme 6 |
| Date | Results | Publications |
|---|---|---|
| 2020-12-05 12:59:00 | Ubiquitination-activating enzymes UBE1 and UBA6 regulate ubiquitination and expression of cardiac sodium channel Nav1.5. | 32315024 |
| 2020-04-11 10:13:00 | These findings demonstrate that UBA6 and BIRC6 negatively regulate autophagy by limiting the availability of LC3B. | 31692446 |
| 2018-11-24 10:24:00 | Polyubiquitination and proteasomal degradation of ezrin and CUGBP1 require Uba6, but not Uba1, and that Uba6 is involved in the control of ezrin localization and epithelial morphogenesis. These data suggest that distinctive substrate pools exist for Uba1 and Uba6 that reflect non-redundant biological roles for Uba6. | 28134249 |
| 2017-06-03 11:46:00 | this study revealed a novel function of LMO2 involving in the regulatory hierarchy of UBA6-USE1-FAT10ylation pathway by targeting the E1 enzyme UBA6. | 27569286 |
| 2016-10-22 11:28:00 | Interstitial microdeletions including the chromosome band 4q13.2 and the UBA6 gene as possible causes of intellectual disability and behavior disorder. | 26284580 |
| Type | IDs |
|---|---|
| Synonymous | E1-L2, MOP-4, UBE1L2 |
| Gene |
UniProtKB-ID:
UBA6_HUMAN,
A1LT96_HUMAN
UniprotKB:
A0AVT1,
A1LT96
UniParc:
UPI0000F0A584,
UPI000004A4F7,
UPI000020B859,
UPI000006F405
EMBL:
AB014773,
AL832015,
AC096720,
BC126484,
AK001670,
EF623993,
AC079880,
BC031637,
AK314371,
AK094969,
AY359880,
AL832458,
BC126486,
CH471057
Ensembl:
ENSG00000033178
KO:
hsa:55236
|
| Nucleutide sequences |
EMBL-CDS:
BAC04463.1,
BAG37000.1,
BAA91824.1,
AAH31637.1,
ABR25253.1,
AAQ63403.1,
AAI26485.1,
CAD89959.1,
BAB19785.1,
AAI26487.1,
CAD89908.1,
AAY40999.1,
EAX05549.1,
EAX05551.1
Gene_ORFName:
hCG_2027425
Ensembl_TRS:
ENST00000420827,
ENST00000322244
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000399234,
ENSP00000313454
RefSeq:
XP_016863848.1,
NP_060697.4
|
| Others |
UniRef100:
UniRef100_A0AVT1
UniRef90:
UniRef90_A0AVT1
UniRef50:
UniRef50_A0AVT1
UniGene:
Hs.212774
CCDS:
CCDS3516.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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