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55234 SMU1

55234

SMU1

SMU1 DNA replication regulator and spliceosomal factor

protein-coding

Homo sapiens

基因描述

Type Description
Definition SMU1 DNA replication regulator and spliceosomal factor

研究结论

Date Results Publications
2020-04-11 12:45:00 Investigated and identified antiviral agents targeting the assembly of the human RED-SMU1 splicing complex, and results demonstrate possibility of RED-SMU1 destabilizing molecules to be used in antiviral therapy. 31076555
2020-01-11 10:03:00 Smu1 and RED function both as alternative splicing regulators and as general splicing factors and are required predominantly for efficient splicing of short introns. 31409787
2019-12-07 11:41:00 Results unveil an important role of CRL7(SMU1) E3 ligase in promoting H2B ubiquitylation for maintenance of sister chromatid cohesion during mitosis. 29507117
2015-08-15 11:27:00 Data suggest that two human spliceosomal factors, SMU1 and RED, are recruited to control expression and alternative splicing of viral exportins via PB2 (polymerase PB2) of influenza A virus (H3N2) and are required for efficient viral multiplication. 24945353
2013-09-21 11:45:00 Data suggest that Smu1 participates in the protection of genomic integrity by negatively regulating the process of DNA synthesis. 23727573

名称对应

Type IDs
Synonymous BWD, SMU-1, fSAP57
Gene
UniProtKB-ID: SMU1_HUMAN, A0MNN4_HUMAN
UniprotKB: Q2TAY7, A0MNN4
UniParc: UPI00017A8771, UPI0000022E9B
EMBL: AL162590, BC110654, BC002876, CH471071, EF011613, AK022032, AK001667, AK304767
Ensembl: ENSG00000122692
KO: hsa:55234
Nucleutide sequences
EMBL-CDS: AAI10655.1, BAA91822.1, BAG65522.1, AAH02876.1, ABK41103.1, EAW58522.1
Gene_ORFName: hCG_30278
Ensembl_TRS: ENST00000397149
Protein sequencees
Ensembl_PRO: ENSP00000380336
RefSeq: XP_005251560.1, NP_060695.2
Others
UniRef100: UniRef100_Q2TAY7
UniRef90: UniRef90_Q2TAY7
UniRef50: UniRef50_Q2TAY7
UniGene: Hs.655351
CCDS: CCDS6534.1

全选

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