| Type | Description |
|---|---|
| Definition | ubiquitin specific peptidase 40 |
| Date | Results | Publications |
|---|---|---|
| 2019-09-07 11:43:00 | Our findings show the de-ubiquitinase USP40 regulates the ubiquitination and degradation of CFLARL; and GMEB1 acts as a bridge protein for USP40 and CFLARL. Mechanistically, we found GMEB1 inhibits the activation of CASP8 by modulating ubiquitination and degradation of CFLARL | 31046799 |
| 2013-03-09 10:25:00 | present study is the first to report a lack of association between SNPs of USP40 and parkinson disease in Han Chinese patients. Other | 22923019 |
| 2010-09-06 12:03:00 | USP24 alone plays a role in PD susceptibility among Taiwanese people >or=60 years of age, or acting synergistically with USP40 and UCHL1 in the total subjects. | 20302855 |
| 2010-04-07 21:40:00 | Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator) | 20302855 |
| 2010-01-21 00:00:00 | Da suggest that genetic variants in USP40 affect the risk for late-onset Parkinson disease (PD), which is consistent with the predicted role of the ubiquitination pathway in PD etiology. | 16917932 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
UBP40_HUMAN
UniprotKB:
Q9NVE5
UniParc:
UPI0000232F06,
UPI00004C8020,
UPI00001C0987
EMBL:
AK001647,
BC067300,
AC019221,
AK124094,
AC019072,
AJ583821
Ensembl:
ENSG00000085982
KO:
hsa:55230
|
| Nucleutide sequences |
EMBL-CDS:
BAC85770.1,
BAA91807.1,
AAH67300.1,
CAE47748.2
Ensembl_TRS:
ENST00000409945,
ENST00000427112,
ENST00000450966,
ENST00000251722
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000415434,
ENSP00000386664,
ENSP00000251722,
ENSP00000387898
RefSeq:
XP_011509700.1,
NP_001369231.1,
NP_001369227.1,
NP_001369232.1,
NP_001369228.1,
NP_060688.2,
NP_001369224.1,
XP_016859917.1,
XP_011509702.1,
XP_006712675.1,
NP_001352408.1,
XP_016859916.1,
NP_001369229.1,
XP_011509699.1,
NP_001369225.1,
NP_001369226.1,
XP_011509698.1,
XP_011509703.1,
NP_001369230.1,
XP_011509701.1
|
| Others |
UniRef100:
UniRef100_Q9NVE5
UniRef90:
UniRef90_Q9NVE5
UniRef50:
UniRef50_Q9NVE5
UniGene:
Hs.96513
CCDS:
CCDS46547.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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