| Type | Description |
|---|---|
| Definition | N-acetyltransferase 10 |
| Date | Results | Publications |
|---|---|---|
| 2020-07-11 12:14:00 | A role for MORC2 in regulating DNA damage-induced G2 checkpoint through NAT10-mediated acetylation. | 32112098 |
| 2019-10-12 10:58:00 | High NAT10 expression is associated with Hutchinson-Gilford progeria syndrome by sequestering TNPO1 in the cytoplasm. | 29970603 |
| 2019-06-29 11:49:00 | we demonstrate that the acetylation status of NAT10 is important for the anabolism-catabolism transition in response to energy stress, providing a novel mechanism by which nucleolar proteins control rRNA synthesis and autophagy in response to the cellular energy supply. | 30165671 |
| 2018-10-13 12:04:00 | immunohistochemistry staining of NAT10 in hepatocellular carcinoma tissues demonstrates that the cytoplasmic NAT10 is correlated with poorer prognosis compared with nuclear NAT10, while the membranous NAT10 predicts the poorest clinical outcome of the patients. | 29634924 |
| 2018-05-12 10:02:00 | Increased NAT10 expression levels are associated with shortened hepatocellular carcinoma (HCC) patient survival and correlated with mutant p53 levels. NAT10 upregulates mutant p53 level and might enhance its tumorigenic activity. Hence, it is proposed that NAT10 could be a potential prognostic and therapeutic candidate for p53-mutated HCC. | 28859621 |
| Type | IDs |
|---|---|
| Synonymous | ALP, Kre33, NET43 |
| Gene |
UniProtKB-ID:
NAT10_HUMAN
UniprotKB:
Q9H0A0
UniParc:
UPI000013CF8E,
UPI0001AE6B62
EMBL:
AK294044,
AL136882,
AB051496,
AK001636,
AC090469,
BC035558,
AK022241,
AF489535
Ensembl:
ENSG00000135372
KO:
hsa:55226
|
| Nucleutide sequences |
EMBL-CDS:
AAH35558.1,
CAB66816.1,
BAA91800.1,
BAB13995.1,
BAB21800.1,
AAO49126.1,
BAG57396.1
Ensembl_TRS:
ENST00000531159,
ENST00000257829
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000433011,
ENSP00000257829
RefSeq:
NP_001137502.2,
NP_078938.3
|
| Others |
UniRef100:
UniRef100_Q9H0A0
UniRef90:
UniRef90_Q9H0A0
UniRef50:
UniRef50_Q9H0A0
UniGene:
Hs.577281
CCDS:
CCDS7889.1,
CCDS44568.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员