| Type | Description |
|---|---|
| Definition | tripartite motif containing 62 |
| Date | Results | Publications |
|---|---|---|
| 2017-12-16 11:04:00 | Results found that TRIM62 was frequently down-regulated in both human cervical cancer (CC) cells and tissues. Low expression of TRIM62 in CC tissues was associated with aggressive clinicopathological features of CC patients. Its overexpression inhibits proliferation, migration and invasion of cervical cancer cells. | 27793172 |
| 2016-02-06 10:32:00 | TRIM62 is a CARD9-binding partner. TRIM62 facilitated K27-linked poly-ubiquitination of CARD9. | 26488816 |
| 2015-10-24 10:22:00 | Low TRIM62 levels, consistent with a tumor suppressor role, represent an independent adverse prognostic factor in AML. | 25248926 |
| 2014-12-27 11:11:00 | DEAR1 is important in the regulation of the breast tumor microenvironment, polarity, and epithelial-mesenchymal transition. [Review] | 25261235 |
| 2014-05-03 10:39:00 | results provide compelling evidence that DEAR1 is a critical tumor suppressor involved in multiple human cancers and provide a novel paradigm for regulation of TGF-beta-induced EMT through DEAR1's regulation of SMAD3 protein levels | 23838884 |
| Type | IDs |
|---|---|
| Synonymous | DEAR1 |
| Gene |
UniProtKB-ID:
TRI62_HUMAN
UniprotKB:
Q9BVG3
UniParc:
UPI000004E050,
UPI00017A7F48
EMBL:
CH471059,
BC007999,
BC001222,
AK300177,
BC011689,
AL662907,
BC012152,
AK122896,
AK001621
Ensembl:
ENSG00000116525
KO:
hsa:55223
|
| Nucleutide sequences |
EMBL-CDS:
BAA91792.1,
AAH07999.1,
BAG53787.1,
EAX07467.1,
BAG61956.1,
AAH11689.1,
EAX07466.1,
AAH01222.1,
AAH12152.1
Ensembl_TRS:
ENST00000291416,
ENST00000543586
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000441173,
ENSP00000291416
RefSeq:
NP_060677.2,
XP_016857120.1,
XP_016857118.1,
XP_016857119.1,
NP_001317412.1
|
| Others |
UniRef100:
UniRef100_Q9BVG3
UniRef90:
UniRef90_Q9BVG3
UniRef50:
UniRef50_Q9BVG3
UniGene:
Hs.656006
CCDS:
CCDS376.1,
CCDS81297.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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