| Type | Description |
|---|---|
| Definition | FA complementation group I |
| Date | Results | Publications |
|---|---|---|
| 2020-06-06 11:37:00 | cryo-electron microscopy structure of the monoubiquitinated human ID complex (involving the proteins FANCI and FANCD2) bound to DNA, and reveal that it forms a closed ring that encircles the DNA | 32269332 |
| 2019-06-29 11:17:00 | show that FANCI localizes to the nucleolus and is functionally and physically tied to the transcription of pre-ribosomal RNA (pre-rRNA) and to large ribosomal subunit (LSU) pre-rRNA processing independent of FANCD2 | 30692263 |
| 2018-12-29 12:02:00 | BRMS1FANCI interaction is necessary for the regulatory role of BRMS1 in the FA pathway. | 30365131 |
| 2018-09-15 10:25:00 | Study reports the first structural insight into the human FANCD2-FANCI complex by obtaining the cryo-EM structure. The complex contains an inner cavity, large enough to accommodate a double-stranded DNA helix, as well as a protruding Tower domain. Disease-causing mutations in the Tower domain are observed in several Fanconi anemia patients. | 27405460 |
| 2018-03-31 10:55:00 | FANCI phosphorylation activates the FANCI/D2 complex. | 28636932 |
| Type | IDs |
|---|---|
| Synonymous | KIAA1794 |
| Gene |
UniProtKB-ID:
FANCI_HUMAN,
B3KNW8_HUMAN
UniprotKB:
Q9NVI1,
B3KNW8
UniParc:
UPI00001A820B,
UPI0000603C25,
UPI00001FEB1D,
UPI00001D77A4,
UPI000181EEE9
EMBL:
AK027564,
BC140769,
AK001581,
BC004277,
AK055176,
EF469766,
AC124068,
EF567077,
AB058697
Ensembl:
ENSG00000140525
KO:
hsa:55215
|
| Nucleutide sequences |
EMBL-CDS:
ABQ63084.1,
AAH04277.1,
AAI40770.1,
BAB55200.1,
ABP88002.1,
BAB47423.1,
BAA91770.1,
BAG51480.1
Ensembl_TRS:
ENST00000300027,
ENST00000310775,
ENST00000567996
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000300027,
ENSP00000458024,
ENSP00000310842
RefSeq:
NP_060663.2,
NP_001363840.1,
XP_011520066.1,
NP_001106849.1,
NP_001363839.1,
XP_011520058.1
|
| Others |
UniRef100:
UniRef100_Q9NVI1,
UniRef100_B3KNW8
UniRef90:
UniRef90_A0A2I2Y249,
UniRef90_Q9NVI1
UniRef50:
UniRef50_L5MBU2,
UniRef50_Q9NVI1
UniGene:
Hs.513126
CCDS:
CCDS45346.1,
CCDS10349.2
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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