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5521 PPP2R2B

5521

PPP2R2B

protein phosphatase 2 regulatory subunit Bbeta

protein-coding

Homo sapiens

基因描述

Type Description
Definition protein phosphatase 2 regulatory subunit Bbeta

研究结论

Date Results Publications
2020-12-05 13:02:00 EZH2-mediated PP2A inactivation confers resistance to HER2-targeted breast cancer therapy. 33208750
2020-07-25 12:56:00 Transcriptional regulation of PPP2R2B (B55ss), a molecule necessary for the termination of the immune response, in patients with autoimmune diseases. PPP2R2B hypermethylation causes acquired apoptosis deficiency in systemic autoimmune diseases. 31335320
2020-06-20 11:16:00 CDK1-counteracting phosphatases PP1 and PP2A-B55, together with Aurora and Polo kinases, contribute to the temporal regulation and order of events in the different stages of mitotic exit from anaphase to cytokinesis. (Review) 31494926
2018-07-14 11:28:00 Dephosphorylation and total levels of beta-catenin were dependent on PR55beta in an adenoid cystic carcinoma tumor cell line. 29275362
2017-06-10 10:28:00 New pathogenic threshold of PPP2R2B CAG-43 to be pathogenic for SCA12 diagnosis. 27864267

名称对应

Type IDs
Synonymous B55BETA, PP2AB55BETA, PP2ABBETA, PP2APR55B, PP2APR55BETA, PR2AB55BETA, PR2ABBETA, PR2APR55BETA, PR52B, PR55-BETA, PR55BETA, SCA12
Gene
UniProtKB-ID: 2ABB_HUMAN
UniprotKB: Q00005
UniParc: UPI0000EE34D6, UPI0001B300FA, UPI00000887CC, UPI0000026156, UPI0002A137C8, UPI000000401C, UPI00005A7962
EMBL: AC091919, AC010251, AC009186, AK056192, AK295347, M64930, AC011386, AC091924, BC031790, AC008728, CH471062, BI490027, AC011357, BI669304, AK289717, AK294659
Ensembl: ENSG00000156475
KO: hsa:5521
Nucleutide sequences
EMBL-CDS: BAH12040.1, EAW61832.1, EAW61835.1, EAW61834.1, EAW61831.1, BAH11838.1, BAF82406.1, EAW61833.1, AAH31790.1, BAG51642.1, AAA36493.1, EAW61829.1
Ensembl_TRS: ENST00000394409, ENST00000394414, ENST00000394413, ENST00000504198, ENST00000453001, ENST00000336640, ENST00000508545, ENST00000394411
Protein sequencees
Ensembl_PRO: ENSP00000431320, ENSP00000421396, ENSP00000377935, ENSP00000336591, ENSP00000377936, ENSP00000377933, ENSP00000398779, ENSP00000377931
RefSeq: NP_001258828.1, NP_858063.1, NP_858060.2, NP_858061.3, NP_001258829.1, NP_858062.1, NP_001258877.1, NP_858064.1
Others
UniRef100: UniRef100_Q00005
UniRef90: UniRef90_Q00005
UniRef50: UniRef50_Q00005
UniGene: Hs.627618, Hs.655213
CCDS: CCDS64281.1, CCDS43380.1, CCDS64282.1, CCDS4284.2, CCDS4283.1

全选

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