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55201 MAP1S

55201

MAP1S

microtubule associated protein 1S

protein-coding

Homo sapiens

基因描述

Type Description
Definition microtubule associated protein 1S

研究结论

Date Results Publications
2017-06-24 11:27:00 Results suggested that microtubule associated protein 1S (MAP1S) were up-regulated among Crohn's disease (CD) patients and MAP1S-related autophagy inhibits apoptosis of intestinal epithelial cells (IECs) through Wnt/beta-catenin signaling pathway which might play a vital role in the protection of intestinal mucosal barrier and inhibition the progression of CD. 28188784
2017-01-28 10:35:00 Autophagy defects in the degradation of lipid droplets triggered by the MAP1S deficiency may enhance the initiation and development of ccRCC and reduce the survival of ccRCC patients. 26701856
2016-09-10 12:02:00 HDAC4 destabilizes MAP1S, suppresses autophagy flux and promotes the accumulation of mHTT aggregates. 26540094
2015-07-25 10:58:00 Ddata underline the key role of MAP1S as a global regulator of microbutule stability and demonstrate a new primary function of MAP1S to regulate MT dynamics at the onset of cytokinesis. 25300793
2015-05-09 11:31:00 results support a role for MAP1 proteins in promoting efficient retrograde trafficking of HIV-1 by stimulating the formation of stable microtubules and mediating the association of HIV-1 cores with microtubules. 25505242

名称对应

Type IDs
Synonymous BPY2IP1, C19orf5, MAP8, VCY2IP-1, VCY2IP1
Gene
UniProtKB-ID: MAP1S_HUMAN
UniprotKB: Q66K74
UniParc: UPI00017A700E, UPI00002036F9
EMBL: AL834233, BC008806, BC007253, AK001531, BC067115, BC113952, AB062430, AK027623, BC080547, DQ387861, BC006358, AJ440784, AC008761, AK023118, AK294936
Ensembl: ENSG00000130479
KO: hsa:55201
Nucleutide sequences
EMBL-CDS: AAH67115.1, AAH08806.2, ABD47682.1, BAG58014.1, AAH80547.1, CAD29574.1, AAH06358.2, AAI13953.1, BAB93493.1, AAH07253.1, CAD38911.1, BAA91743.1, BAB55242.1, BAB14415.1
Ensembl_TRS: ENST00000544059, ENST00000324096
Protein sequencees
Ensembl_PRO: ENSP00000325313, ENSP00000439243
RefSeq: XP_016882419.1, NP_060644.4, NP_001295292.1, XP_016882420.1
Others
UniRef100: UniRef100_Q66K74
UniRef90: UniRef90_Q66K74
UniRef50: UniRef50_Q66K74
UniGene: Hs.66048
CCDS: CCDS32954.1, CCDS77262.1

全选

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