| Type | Description |
|---|---|
| Definition | RIC8 guanine nucleotide exchange factor B |
| Date | Results | Publications |
|---|---|---|
| 2017-09-16 10:48:00 | these data show the existence of functional CREB and C/EBP binding sites in the human RIC8B gene promoter, a particular distribution of these sites and demonstrate a relevant role of CREB in stimulating transcriptional activity of this gene. | 26729411 |
| 2017-08-05 10:45:00 | overexpression of ARMS blocked NGF-mediated secretion, without affecting basal secretion, a decrease in ARMS resulted in potentiation. Similar effects were observed with synembryn-B, a protein that interacts directly with ARMS. Downstream of ARMS and synembryn-B are Galphaq and Trio proteins, which modulate the activity of Rac1 in response to NGF | 26966186 |
| 2010-05-10 11:38:00 | Ric-8B plays a critical and specific role in the control of G alpha(s) protein levels by modulating G alpha(s) ubiquitination and positively regulates G(s) signaling | 20133939 |
| 2010-01-21 00:00:00 | We identified a protein member of the synembryn family as one of the interacting proteins in human brain. Gqalpha also interacts with synembryn. Synembryn translocates to the plasma membrane in response to carbachol and isoproterenol. | 12652642 |
| Type | IDs |
|---|---|
| Synonymous | RIC8, hSyn |
| Gene |
UniProtKB-ID:
RIC8B_HUMAN,
B7WPL0_HUMAN,
A0A024RBG9_HUMAN
UniprotKB:
Q9NVN3,
B7WPL0,
A0A024RBG9
UniParc:
UPI0000070DDB,
UPI00001C0F4F,
UPI000013F7F5,
UPI00001FB46B,
UPI00001FB46D
EMBL:
BC034220,
AK128102,
AK001482,
BC144056,
AC007695,
AC090011,
AY221116,
CH471054,
BC132689,
AC079385
Ensembl:
ENSG00000111785
KO:
hsa:55188
|
| Nucleutide sequences |
EMBL-CDS:
AAO65923.1,
AAI44057.1,
AAH34220.1,
BAA91717.1,
AAI32690.1,
EAW97786.1,
EAW97785.1
Gene_ORFName:
hCG_16105
Ensembl_TRS:
ENST00000462949,
ENST00000355478,
ENST00000470960,
ENST00000392839,
ENST00000392837
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000435301,
ENSP00000376583,
ENSP00000347662,
ENSP00000436359,
ENSP00000376582
RefSeq:
NP_001317074.1,
NP_001338293.1,
NP_001317076.1,
NP_001317075.1,
NP_060627.2,
NP_001338291.1,
NP_001338290.1,
NP_001338292.1,
NP_001338296.1,
NP_001338295.1
|
| Others |
UniRef100:
UniRef100_B7WPL0,
UniRef100_Q9NVN3,
UniRef100_A0A024RBG9
UniRef90:
UniRef90_Q9NVN3,
UniRef90_A0A3Q1M9J6
UniRef50:
UniRef50_Q9NVN3
UniGene:
Hs.131306
CCDS:
CCDS86331.1,
CCDS81733.1,
CCDS9109.2
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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