| Type | Description |
|---|---|
| Definition | ring finger and WD repeat domain 3 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-20 13:27:00 | E3 ligase RFWD3 is a novel modulator of stalled fork stability in BRCA2-deficient cells. | 32391871 |
| 2021-03-13 13:16:00 | Identification of an E3 ligase-encoding gene RFWD3 in non-small cell lung cancer. | 31571161 |
| 2021-02-27 13:51:00 | The ubiquitin ligase RFWD3 is required for translesion DNA synthesis. | 33321094 |
| 2020-11-28 13:16:00 | Down-regulation of RFWD3 inhibits cancer cells proliferation and migration in gastric carcinoma. | 32902405 |
| 2017-10-14 12:38:00 | The results suggest that RPA phosphorylation enhances the recruitment of PRP19 to RPA-ssDNA and stimulates RPA ubiquitylation through a process requiring both PRP19 and RFWD3, thereby triggering a phosphorylation-ubiquitylation circuitry that promotes ATR activation and homologous recombination. | 28666352 |
| Type | IDs |
|---|---|
| Synonymous | FANCW, RNF201 |
| Gene |
UniProtKB-ID:
RFWD3_HUMAN
UniprotKB:
Q6PCD5
UniParc:
UPI0000366B66
EMBL:
AK001382,
AC109599,
BC002574,
BC059371,
AK315786,
AK022673,
CH471114,
AK291200
Ensembl:
ENSG00000168411
KO:
hsa:55159
|
| Nucleutide sequences |
EMBL-CDS:
BAA91662.1,
AAH59371.2,
BAG38132.1,
EAW95680.1,
AAH02574.2,
BAF83889.1,
EAW95681.1,
BAB14169.1
Ensembl_TRS:
ENST00000361070,
ENST00000571750
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000460049,
ENSP00000354361
RefSeq:
XP_006721291.1,
NP_001357463.1,
NP_060594.3,
NP_001357465.1,
XP_016878880.1,
XP_011521493.1,
NP_001357466.1,
NP_001357471.1,
NP_001357469.1,
NP_001357464.1,
NP_001357468.1,
NP_001357472.1,
XP_005256079.1
|
| Others |
UniRef100:
UniRef100_Q6PCD5
UniRef90:
UniRef90_Q6PCD5
UniRef50:
UniRef50_Q6PCD5
UniGene:
Hs.567525
CCDS:
CCDS32486.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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