Type | Description |
---|---|
Definition | mitochondrial poly(A) polymerase |
Date | Results | Publications |
---|---|---|
2019-07-20 11:24:00 | These results indicate that NDP52 and MTPAP form an autophagy receptor complex, which enhances autophagic elimination of damaged mitochondria. | 30309841 |
2016-04-02 11:59:00 | Mitochondrial poly(A) polymerase is able to add the discriminator adenosine to tRNATyr. | 26354863 |
2015-10-31 11:37:00 | The polymerase activity of mtPAP is modulated by LRPPRC/SLIRP; N478D mtPAP mutation decreases its activity and the alteration in poly(A) length causes dysregulation of post-transcriptional expression and lack of respiratory chain complexes. | 25008111 |
2014-10-25 12:08:00 | Mutation of the MTPAP gene results in a cellular phenotype of increased DNA damage, reduced repair kinetics, increased cell death by apoptosis, and reduced clonogenic survival after exposure to ionizing radiation. | 24651433 |
2011-04-09 10:39:00 | show that dimerization is required for the catalytic activity of PAPD1 | 21292163 |
Type | IDs |
---|---|
Synonymous | PAPD1, SPAX4, TENT6 |
Gene |
UniProtKB-ID:
PAPD1_HUMAN
UniprotKB:
Q9NVV4
UniParc:
UPI000013EBEC,
UPI0000070081
EMBL:
AK001348,
AK022188,
AL122121,
AL353796,
AB194709,
AY364242,
CH471072,
BC061703,
AL161651
Ensembl:
ENSG00000107951
KO:
hsa:55149
|
Nucleutide sequences |
EMBL-CDS:
AAQ76801.1,
CAH56395.1,
BAD98252.1,
BAB13981.1,
BAA91641.1,
EAW86014.1,
AAH61703.1,
EAW86015.1
Ensembl_TRS:
ENST00000263063
|
Protein sequencees |
Ensembl_PRO:
ENSP00000263063
RefSeq:
NP_060579.3
|
Others |
UniRef100:
UniRef100_Q9NVV4
UniRef90:
UniRef90_Q9NVV4
UniRef50:
UniRef50_Q9NVV4
UniGene:
Hs.173946
CCDS:
CCDS7165.1
|
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