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55140 ELP3

55140

ELP3

elongator acetyltransferase complex subunit 3

protein-coding

Homo sapiens

基因描述

Type Description
Definition elongator acetyltransferase complex subunit 3

研究结论

Date Results Publications
2020-03-21 11:25:00 study reveals a novel regulatory mechanism for ELP3, provides an example that acetyltransferase itself can be regulated by PTM, and suggests a potential target for ALK-positive cancer therapies. 31341009
2019-07-20 11:00:00 Elongator activated migration and invasion of hepatocellular carcinoma cells by promoting the expression of MMP-2 and MMP-9 through the PI3K/AKT signaling pathway 29805303
2017-08-05 10:32:00 and CTU1/2, partner enzymes in U34 methoxycarbonylmethyl-2-thio tRNA modification, are up-regulated in human breast cancers and sustain metastasis. 27811057
2015-10-10 11:25:00 Promoter hypermethylation is an important mechanism of the transcriptional inactivation of ELP3 in invasive ductal breast carcinoma. 25148870
2014-08-16 11:27:00 Regulation of G6PD acetylation by SIRT2 and KAT9 modulates NADPH homeostasis and cell survival during oxidative stress. 24769394

名称对应

Type IDs
Synonymous KAT9
Gene
UniProtKB-ID: ELP3_HUMAN, B4DXV1_HUMAN, B4DKA4_HUMAN
UniprotKB: Q9H9T3, B4DXV1, B4DKA4
UniParc: UPI000006F0B5, UPI00017A6C42, UPI00017A75C0, UPI0000F6E6EC, UPI00017A82F2, UPI00017A734C
EMBL: AL834273, AK022626, AK295574, AK296475, BX648011, AC019031, BC001240, AK315985, AK223047, AK316053, AC021678, AK302140, AK001284, AK293424
Ensembl: ENSG00000134014
KO: hsa:55140
Nucleutide sequences
EMBL-CDS: CAH10573.1, CAD38948.1, BAG56930.1, AAH01240.1, BAB14138.1, BAD96767.1, BAA91600.1, BAG58473.1, BAH14356.1, BAG63513.1, BAG59116.1, BAH14424.1
Ensembl_TRS: ENST00000380353, ENST00000256398, ENST00000521015, ENST00000537665, ENST00000524103
Protein sequencees
Ensembl_PRO: ENSP00000256398, ENSP00000445558, ENSP00000369711, ENSP00000428449, ENSP00000429180
RefSeq: XP_024302952.1, NP_001271149.1, NP_001271153.1, NP_060561.3, NP_001271154.1, NP_001271155.1, XP_016869093.1, XP_006716417.1, XP_024302953.1, NP_001271151.1
Others
UniRef100: UniRef100_Q9H9T3, UniRef100_B4DXV1
UniRef90: UniRef90_Q9H9T3, UniRef90_A0A3Q2H9G4
UniRef50: UniRef50_T1G4A2, UniRef50_Q9H9T3
UniGene: Hs.491336
CCDS: CCDS75717.1, CCDS64861.1, CCDS6065.1, CCDS64860.1

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