| Type | Description |
|---|---|
| Definition | protein phosphatase 1 regulatory subunit 10 |
| Date | Results | Publications |
|---|---|---|
| 2021-02-06 13:53:00 | Upregulation of Phosphatase 1 Nuclear-Targeting Subunit (PNUTS) Is an Independent Predictor of Poor Prognosis in Prostate Cancer. | 32377272 |
| 2020-02-22 12:07:00 | Poly(A) site-dependent deceleration caused by PNUTS-PP1 and Spt5 dephosphorylation is required to convert Pol II into a viable target for the Xrn2 terminator exonuclease, leading to transcription termination. | 31677974 |
| 2020-01-25 14:17:00 | PNUTS depletion suppresses the activation of Aurora A/B kinases, and disrupts the spatiotemporal regulation of the chromosomal passenger complex (CPC). PNUTS dynamically localizes to kinetochores, and is required for the activation of the spindle assembly checkpoint. | 30190438 |
| 2018-12-22 10:31:00 | The work demonstrates that PP1/PNUTS stabilizes chromatin-bound MYC in proliferating cells. | 30158517 |
| 2018-11-03 11:44:00 | A -31 G to A "hot zone" putative functional noncoding variant of PPP1R10 was found in an AML patient. It perturbs the binding activities of E2F1, E2F4, ZBTB33, and TBP. SRSF1 and PPP1R10 genes are interacting partners in a protein-protein interaction network. | 29764005 |
| Type | IDs |
|---|---|
| Synonymous | CAT53, FB19, PNUTS, PP1R10, R111, p99 |
| Gene |
UniProtKB-ID:
PP1RA_HUMAN,
Q2L6I0_HUMAN
UniprotKB:
Q96QC0,
Q2L6I0
UniParc:
UPI000000D73C
EMBL:
BA000025,
KY500565,
KY500563,
AB088097,
KY500564,
AJ544537,
KY500562,
KY500561,
KY500567,
AB103603,
KY500566,
AL662800,
BX248507,
AB202094,
Y13247,
AL662825,
BC136294,
HM005690,
CH471081
Ensembl:
ENSG00000204569,
ENSG00000238104,
ENSG00000231737,
ENSG00000235291,
ENSG00000227804,
ENSG00000206489,
ENSG00000230995
KO:
hsa:5514
|
| Nucleutide sequences |
EMBL-CDS:
BAB63324.1,
CAA73697.1,
CAD67521.1,
BAC54929.1,
AQY77036.2,
AQY77038.1,
AEE61287.1,
BAE78613.1,
AQY77037.1,
BAF31264.1,
AQY77039.1,
AQY77035.1,
AQY77034.1,
AQY77033.1,
EAX03303.1,
AAI36295.1
Gene_ORFName:
hCG_26006
Ensembl_TRS:
ENST00000429597,
ENST00000376511,
ENST00000424446,
ENST00000383586,
ENST00000420949,
ENST00000449113,
ENST00000426299
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000413554,
ENSP00000407181,
ENSP00000389299,
ENSP00000365694,
ENSP00000373080,
ENSP00000416060,
ENSP00000407310
RefSeq:
NP_002705.2,
XP_011513024.1,
XP_006715193.1,
XP_016866484.1,
NP_001363124.1
|
| Others |
UniRef100:
UniRef100_Q96QC0
UniRef90:
UniRef90_Q96QC0
UniRef50:
UniRef50_Q96QC0
UniGene:
Hs.106019
CCDS:
CCDS4681.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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