| Type | Description |
|---|---|
| Definition | fidgetin, microtubule severing factor |
| Date | Results | Publications |
|---|---|---|
| 2017-09-16 12:23:00 | FIGN might play an important role in decreased congenital heart defect risk by upregulating plasma folate concentration during embryo heart development | 28534241 |
| 2017-08-19 12:38:00 | FIGN +94762G>C polymorphism reduced the risk of congenital heart defects by activating the transcription of an alternative FIGN isoform, inhibiting proteasome activity and allowing the accumulation of RFC1 and DHFR, promoting folate transmembrane transport and utilization. | 28302752 |
| 2012-10-20 10:51:00 | The loss of Fidgetin induces a microtubule-dependent enlargement of mitotic centrosomes and an increase in the number and length of astral microtubules. | 22672901 |
| 2010-09-15 22:06:00 | Observational study of gene-disease association. (HuGE Navigator) | 19913121 |
| 2010-09-15 22:06:00 | Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator) | 20628086 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
FIGN_HUMAN
UniprotKB:
Q5HY92
UniParc:
UPI000022BD13
EMBL:
BX649105,
AC093727,
AK001267,
AK025747,
AK125324
Ensembl:
ENSG00000182263
KO:
hsa:55137
|
| Nucleutide sequences |
EMBL-CDS:
AAX81992.1,
BAB15231.1,
CAI45980.1,
BAA91590.1,
BAG54182.1
Ensembl_TRS:
ENST00000333129
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000333836
RefSeq:
XP_016859908.1,
NP_001308754.1,
XP_011509691.1,
NP_060556.2
|
| Others |
UniRef100:
UniRef100_Q5HY92
UniRef90:
UniRef90_Q9ERZ6
UniRef50:
UniRef50_Q9ERZ6
UniGene:
Hs.593650
CCDS:
CCDS2221.2
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 32296183 |
A reference map of the human binary protein interactome. Nature Katja Luck , Dae-Kyum Kim , Luke Lambourne , Kerstin Spirohn , Bridget E Begg , Wenting Bian , Ruth Brignall , Tiziana Cafarelli , Francisco J Campos-Laborie , Benoit Charloteaux , Dongsic Choi , Atina G Coté , Meaghan Daley , Steven Deimling , Alice Desbuleux , Amélie Dricot , Marinella Gebbia , Madeleine F Hardy , Nishka Kishore , Jennifer J Knapp , István A Kovács , Irma Lemmens , Miles W Mee , Joseph C Mellor , Carl Pollis , Carles Pons , Aaron D Richardson , Sadie Schlabach , Bridget Teeking , Anupama Yadav , Mariana Babor , Dawit Balcha , Omer Basha , Christian Bowman-Colin , Suet-Feung Chin , Soon Gang Choi , Claudia Colabella , Georges Coppin , Cassandra D'Amata , David De Ridder , Steffi De Rouck , Miquel Duran-Frigola , Hanane Ennajdaoui , Florian Goebels , Liana Goehring , Anjali Gopal , Ghazal Haddad , Elodie Hatchi , Mohamed Helmy , Yves Jacob , Yoseph Kassa , Serena Landini , Roujia Li , Natascha van Lieshout , Andrew MacWilliams , Dylan Markey , Joseph N Paulson , Sudharshan Rangarajan , John Rasla , Ashyad Rayhan , Thomas Rolland , Adriana San-Miguel , Yun Shen , Dayag Sheykhkarimli , Gloria M Sheynkman , Eyal Simonovsky , Murat TaÅan , Alexander Tejeda , Vincent Tropepe , Jean-Claude Twizere , Yang Wang , Robert J Weatheritt , Jochen Weile , Yu Xia , Xinping Yang , Esti Yeger-Lotem , Quan Zhong , Patrick Aloy , Gary D Bader , Javier De Las Rivas , Suzanne Gaudet , Tong Hao , Janusz Rak , Jan Tavernier , David E Hill , Marc Vidal , Frederick P Roth , Michael A Calderwood |
2020-04-01 | - |
| 31586073 |
The midbody interactome reveals unexpected roles for PP1 phosphatases in cytokinesis. Nat Commun Luisa Capalbo , Zuni I Bassi , Marco Geymonat , Sofia Todesca , Liviu Copoiu , Anton J Enright , Giuliano Callaini , Maria Giovanna Riparbelli , Lu Yu , Jyoti S Choudhary , Enrico Ferrero , Sally Wheatley , Max E Douglas , Masanori Mishima , Pier Paolo D'Avino |
2019-10-04 | - |
| 29507755 |
Cell Discov Yanan Yue , Jun Liu , Xiaolong Cui , Jie Cao , Guanzheng Luo , Zezhou Zhang , Tao Cheng , Minsong Gao , Xiao Shu , Honghui Ma , Fengqin Wang , Xinxia Wang , Bin Shen , Yizhen Wang , Xinhua Feng , Chuan He , Jianzhao Liu |
2018-01-01 | - |
| 28534241 |
Pediatr Cardiol Dan Wang , Maoping Chu , Feng Wang , Aihua Zhou , Miaohua Ruan , Yiming Chen |
2017-08-01 | - |
| 28514442 |
Architecture of the human interactome defines protein communities and disease networks. Nature Edward L Huttlin , Raphael J Bruckner , Joao A Paulo , Joe R Cannon , Lily Ting , Kurt Baltier , Greg Colby , Fana Gebreab , Melanie P Gygi , Hannah Parzen , John Szpyt , Stanley Tam , Gabriela Zarraga , Laura Pontano-Vaites , Sharan Swarup , Anne E White , Devin K Schweppe , Ramin Rad , Brian K Erickson , Robert A Obar , K G Guruharsha , Kejie Li , Spyros Artavanis-Tsakonas , Steven P Gygi , J Wade Harper |
2017-05-25 | - |
| 28302752 |
Circulation Dan Wang , Feng Wang , Kai-Hu Shi , Hui Tao , Yang Li , Rui Zhao , Han Lu , Wenyuan Duan , Bin Qiao , Shi-Min Zhao , Hongyan Wang , Jian-Yuan Zhao |
2017-05-02 | - |
| 26186194 |
The BioPlex Network: A Systematic Exploration of the Human Interactome. Cell Edward L Huttlin , Lily Ting , Raphael J Bruckner , Fana Gebreab , Melanie P Gygi , John Szpyt , Stanley Tam , Gabriela Zarraga , Greg Colby , Kurt Baltier , Rui Dong , Virginia Guarani , Laura Pontano Vaites , Alban Ordureau , Ramin Rad , Brian K Erickson , Martin Wühr , Joel Chick , Bo Zhai , Deepak Kolippakkam , Julian Mintseris , Robert A Obar , Tim Harris , Spyros Artavanis-Tsakonas , Mathew E Sowa , Pietro De Camilli , Joao A Paulo , J Wade Harper , Steven P Gygi |
2015-07-16 | - |
| 24954895 |
Am J Hum Genet Jeannette Simino , Gang Shi , Joshua C Bis , Daniel I Chasman , Georg B Ehret , Xiangjun Gu , Xiuqing Guo , Shih-Jen Hwang , Eric Sijbrands , Albert V Smith , Germaine C Verwoert , Jennifer L Bragg-Gresham , Gemma Cadby , Peng Chen , Ching-Yu Cheng , Tanguy Corre , Rudolf A de Boer , Anuj Goel , Toby Johnson , Chiea-Chuen Khor , LifeLines Cohort Study , Carla LluÃs-Ganella , Jian'an Luan , Leo-Pekka Lyytikäinen , Ilja M Nolte , Xueling Sim , Siim Sõber , Peter J van der Most , Niek Verweij , Jing Hua Zhao , Najaf Amin , Eric Boerwinkle , Claude Bouchard , Abbas Dehghan , Gudny Eiriksdottir , Roberto Elosua , Oscar H Franco , Christian Gieger , Tamara B Harris , Serge Hercberg , Albert Hofman , Alan L James , Andrew D Johnson , Mika Kähönen , Kay-Tee Khaw , Zoltan Kutalik , Martin G Larson , Lenore J Launer , Guo Li , Jianjun Liu , Kiang Liu , Alanna C Morrison , Gerjan Navis , Rick Twee-Hee Ong , George J Papanicolau , Brenda W Penninx , Bruce M Psaty , Leslie J Raffel , Olli T Raitakari , Kenneth Rice , Fernando Rivadeneira , Lynda M Rose , Serena Sanna , Robert A Scott , David S Siscovick , Ronald P Stolk , Andre G Uitterlinden , Dhananjay Vaidya , Melanie M van der Klauw , Ramachandran S Vasan , Eranga Nishanthie Vithana , Uwe Völker , Henry Völzke , Hugh Watkins , Terri L Young , Tin Aung , Murielle Bochud , Martin Farrall , Catharina A Hartman , Maris Laan , Edward G Lakatta , Terho Lehtimäki , Ruth J F Loos , Gavin Lucas , Pierre Meneton , Lyle J Palmer , Rainer Rettig , Harold Snieder , E Shyong Tai , Yik-Ying Teo , Pim van der Harst , Nicholas J Wareham , Cisca Wijmenga , Tien Yin Wong , Myriam Fornage , Vilmundur Gudnason , Daniel Levy , Walter Palmas , Paul M Ridker , Jerome I Rotter , Cornelia M van Duijn , Jacqueline C M Witteman , Aravinda Chakravarti , Dabeeru C Rao |
2014-07-03 | - |
| 22672901 |
Cell Cycle Suranjana Mukherjee , J Daniel Diaz Valencia , Shannon Stewman , Jeremy Metz , Sylvain Monnier , Uttama Rath , Ana B Asenjo , Rabab A Charafeddine , Hernando J Sosa , Jennifer L Ross , Ao Ma , David J Sharp |
2012-06-15 | - |
| 21909110 |
Nat Genet Louise V Wain , Germaine C Verwoert , Paul F O'Reilly , Gang Shi , Toby Johnson , Andrew D Johnson , Murielle Bochud , Kenneth M Rice , Peter Henneman , Albert V Smith , Georg B Ehret , Najaf Amin , Martin G Larson , Vincent Mooser , David Hadley , Marcus Dörr , Joshua C Bis , Thor Aspelund , Tõnu Esko , A Cecile J W Janssens , Jing Hua Zhao , Simon Heath , Maris Laan , Jingyuan Fu , Giorgio Pistis , Jian'an Luan , Pankaj Arora , Gavin Lucas , Nicola Pirastu , Irene Pichler , Anne U Jackson , Rebecca J Webster , Feng Zhang , John F Peden , Helena Schmidt , Toshiko Tanaka , Harry Campbell , Wilmar Igl , Yuri Milaneschi , Jouke-Jan Hottenga , Veronique Vitart , Daniel I Chasman , Stella Trompet , Jennifer L Bragg-Gresham , Behrooz Z Alizadeh , John C Chambers , Xiuqing Guo , Terho Lehtimäki , Brigitte Kühnel , Lorna M Lopez , Ozren Polašek , Mladen Boban , Christopher P Nelson , Alanna C Morrison , Vasyl Pihur , Santhi K Ganesh , Albert Hofman , Suman Kundu , Francesco U S Mattace-Raso , Fernando Rivadeneira , Eric J G Sijbrands , Andre G Uitterlinden , Shih-Jen Hwang , Ramachandran S Vasan , Thomas J Wang , Sven Bergmann , Peter Vollenweider , Gérard Waeber , Jaana Laitinen , Anneli Pouta , Paavo Zitting , Wendy L McArdle , Heyo K Kroemer , Uwe Völker , Henry Völzke , Nicole L Glazer , Kent D Taylor , Tamara B Harris , Helene Alavere , Toomas Haller , Aime Keis , Mari-Liis Tammesoo , Yurii Aulchenko , Inês Barroso , Kay-Tee Khaw , Pilar Galan , Serge Hercberg , Mark Lathrop , Susana Eyheramendy , Elin Org , Siim Sõber , Xiaowen Lu , Ilja M Nolte , Brenda W Penninx , Tanguy Corre , Corrado Masciullo , Cinzia Sala , Leif Groop , Benjamin F Voight , Olle Melander , Christopher J O'Donnell , Veikko Salomaa , Adamo Pio d'Adamo , Antonella Fabretto , Flavio Faletra , Sheila Ulivi , Fabiola M Del Greco , Maurizio Facheris , Francis S Collins , Richard N Bergman , John P Beilby , Joseph Hung , A William Musk , Massimo Mangino , So-Youn Shin , Nicole Soranzo , Hugh Watkins , Anuj Goel , Anders Hamsten , Pierre Gider , Marisa Loitfelder , Marion Zeginigg , Dena Hernandez , Samer S Najjar , Pau Navarro , Sarah H Wild , Anna Maria Corsi , Andrew Singleton , Eco J C de Geus , Gonneke Willemsen , Alex N Parker , Lynda M Rose , Brendan Buckley , David Stott , Marco Orru , Manuela Uda , LifeLines Cohort Study , Melanie M van der Klauw , Weihua Zhang , Xinzhong Li , James Scott , Yii-Der Ida Chen , Gregory L Burke , Mika Kähönen , Jorma Viikari , Angela Döring , Thomas Meitinger , Gail Davies , John M Starr , Valur Emilsson , Andrew Plump , Jan H Lindeman , Peter A C 't Hoen , Inke R König , EchoGen consortium , Janine F Felix , Robert Clarke , Jemma C Hopewell , Halit Ongen , Monique Breteler , Stéphanie Debette , Anita L Destefano , Myriam Fornage , AortaGen Consortium , Gary F Mitchell , CHARGE Consortium Heart Failure Working Group , Nicholas L Smith , KidneyGen consortium , Hilma Holm , Kari Stefansson , Gudmar Thorleifsson , Unnur Thorsteinsdottir , CKDGen consortium , Cardiogenics consortium , CardioGram , Nilesh J Samani , Michael Preuss , Igor Rudan , Caroline Hayward , Ian J Deary , H-Erich Wichmann , Olli T Raitakari , Walter Palmas , Jaspal S Kooner , Ronald P Stolk , J Wouter Jukema , Alan F Wright , Dorret I Boomsma , Stefania Bandinelli , Ulf B Gyllensten , James F Wilson , Luigi Ferrucci , Reinhold Schmidt , Martin Farrall , Tim D Spector , Lyle J Palmer , Jaakko Tuomilehto , Arne Pfeufer , Paolo Gasparini , David Siscovick , David Altshuler , Ruth J F Loos , Daniela Toniolo , Harold Snieder , Christian Gieger , Pierre Meneton , Nicholas J Wareham , Ben A Oostra , Andres Metspalu , Lenore Launer , Rainer Rettig , David P Strachan , Jacques S Beckmann , Jacqueline C M Witteman , Jeanette Erdmann , Ko Willems van Dijk , Eric Boerwinkle , Michael Boehnke , Paul M Ridker , Marjo-Riitta Jarvelin , Aravinda Chakravarti , Goncalo R Abecasis , Vilmundur Gudnason , Christopher Newton-Cheh , Daniel Levy , Patricia B Munroe , Bruce M Psaty , Mark J Caulfield , Dabeeru C Rao , Martin D Tobin , Paul Elliott , Cornelia M van Duijn |
2011-09-11 | - |
| 排名 | 科研单位 | 文献 |
|---|---|---|
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|---|---|---|
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