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55135 WRAP53

55135

WRAP53

WD repeat containing antisense to TP53

protein-coding

Homo sapiens

基因描述

Type Description
Definition WD repeat containing antisense to TP53

研究结论

Date Results Publications
2021-04-03 13:31:00 Biallelic mutations in WRAP53 result in dysfunctional telomeres, Cajal bodies and DNA repair, thereby causing Hoyeraal-Hreidarsson syndrome. 32303682
2020-03-14 11:10:00 analyze a haplotype comprising four SNPs, including rs1042522, rs17878362, rs2287499, and rs2287498, which are located at 5' regions of the TP53 and WRAP53 genes as molecular prognostic and predictive biomarkers for breast cancer. 31387111
2019-10-26 11:40:00 These findings reveal that WDR79 is a novel UHRF1 regulator by maintaining UHRF1 stability. 29516630
2019-10-19 12:53:00 we suggest that TDP-43 and WDR79 have separate roles in determining Cajal bodies (CBs) localization of subsets of C/D and H/ACA scaRNAs. 30759234
2019-01-12 10:09:00 Data show that up-regulated expression of telomerase Cajal body protein 1 (TCAB1), induced by Epstein-Barr virus (EBV) in the development of nasopharyngeal carcinoma (NPC), is involved in stimulating telomerase activity and regulating the DNA damage response. 28607398

名称对应

Type IDs
Synonymous DKCB3, TCAB1, WDR79
Gene
UniProtKB-ID: TCAB1_HUMAN
UniprotKB: Q9BUR4
UniParc: UPI000007261E
EMBL: DQ431240, AY766322, CH471108, DQ431241, AK056669, AK001247, BC002336
Ensembl: ENSG00000141499
KO: hsa:55135
Nucleutide sequences
EMBL-CDS: BAA91579.1, AAW92115.1, BAG51781.1, EAW90138.1, AAH02336.1, EAW90136.1, EAW90139.1, ABD92818.1, ABD92817.1
Ensembl_TRS: ENST00000316024, ENST00000457584, ENST00000396463, ENST00000431639
Protein sequencees
Ensembl_PRO: ENSP00000379727, ENSP00000324203, ENSP00000411061, ENSP00000397219
RefSeq: NP_001137463.1, NP_060551.2, XP_024306592.1, NP_001137464.1, XP_011522254.1, NP_001137462.1, XP_024306593.1
Others
UniRef100: UniRef100_Q9BUR4
UniRef90: UniRef90_Q9BUR4
UniRef50: UniRef50_Q9BUR4
UniGene: Hs.408312
CCDS: CCDS11119.1

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