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55124 PIWIL2

55124

PIWIL2

piwi like RNA-mediated gene silencing 2

protein-coding

Homo sapiens

基因描述

Type Description
Definition piwi like RNA-mediated gene silencing 2

研究结论

Date Results Publications
2020-12-05 13:04:00 Generation of an iPSC line (HUSTi002-A) from fibroblasts of a patient with Sertoli cell-only syndrome carrying c.731_732delAT in PIWIL2 gene. 32006804
2020-07-11 12:57:00 By up-regulating CTNNB1 and CCND1, PIWIL2 can promote cell cycle and proliferation in tumor cells. 31262447
2020-03-28 10:57:00 PIWIL2 interacts with HDAC3 and promotes the stability and phosphorylation of HDAC3. PIWIL2 can play a role in HDAC3-mediated epigenetic regulation on cancer cell proliferation and apoptosis. 29555935
2020-03-28 10:54:00 Findings showed that PIWIL2 can predict effectively OSCC prognosis and OL with a high risk of OSCC development and substantiate the deduction that cancer stem(-like) cells in oral cancer have the ability to reconstitute the heterogeneity of the bulk tumor and contribute to poor outcome and immunosuppression. 31322538
2019-10-19 10:54:00 Piwi-like 1 and -2 positivity are associated with clinico-pathological factors and survival. Both Piwi-like proteins are suggested as biomarkers for MIBC patients. 30523270

名称对应

Type IDs
Synonymous CT80, HILI, PIWIL1L, mili
Gene
UniProtKB-ID: PIWL2_HUMAN, W0HK13_HUMAN
UniprotKB: Q8TC59, W0HK13
UniParc: UPI000195115D, UPI000006E98E
EMBL: BC025995, BC111751, AK291038, AK027497, AK299068, HQ651229, AK001213, KF651165, AK315833, HM005454, AB079367, AK315830, AK292440
Ensembl: ENSG00000197181
KO: hsa:55124
Nucleutide sequences
EMBL-CDS: AAH25995.1, ADV17663.1, AAI11752.1, BAC81342.1, BAF98721.1, BAG61134.1, BAF98724.1, BAB55155.1, BAA91558.1, BAF85129.1, BAF83727.1, AHF72552.1, AEE61052.1
Ensembl_TRS: ENST00000454009, ENST00000611073, ENST00000521356, ENST00000356766
Protein sequencees
Ensembl_PRO: ENSP00000428267, ENSP00000406956, ENSP00000349208, ENSP00000478103
RefSeq: XP_005273608.1, NP_060538.2, NP_001129193.1, NP_001317409.1
Others
UniRef100: UniRef100_Q8TC59
UniRef90: UniRef90_Q8TC59
UniRef50: UniRef50_Q8TC59
UniGene: Hs.614809
CCDS: CCDS83261.1, CCDS6029.1

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