| Type | Description |
|---|---|
| Definition | cartilage acidic protein 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-20 13:29:00 | Down-regulation of CRTAC1 attenuates UVB-induced pyroptosis in HLECs through inhibiting production. | 32838966 |
| 2020-12-19 13:42:00 | Cartilage acidic protein 1 promotes increased cell viability, cell proliferation and energy metabolism in primary human dermal fibroblasts. | 32084494 |
| 2020-04-18 10:19:00 | CRTAC1 expression and nuclear factor-kappa B (NF-kappaB) p65 nuclear translocation were elevated in capsule tissues of cataract patients in comparison with normal controls. The regulatory network involving NF-kappaB, CRTAC1, and p38 may therefore play an important role in cataract formation. | 31999475 |
| 2019-04-13 12:26:00 | CSF levels of LOTUS correlated inversely with disease activity in both bacterial and viral meningitis; neuroinflammation down-regulated LOTUS expression. | 29454354 |
| 2017-07-29 13:11:00 | Confirm the increase of CRTAC1 in cartilage biopsies from OA patients undergoing joint replacement by real-time PCR and immunohistochemistry. Furthermore, we report that proinflammatory cytokines interleukin-1beta and tumor necrosis factor alpha upregulate CRTAC1 expression in primary articular chondrocytes and synovial fibroblasts. | 27415616 |
| Type | IDs |
|---|---|
| Synonymous | ASPIC, ASPIC1, CEP-68, CEP68, LOTUS |
| Gene |
UniProtKB-ID:
CRAC1_HUMAN
UniprotKB:
Q9NQ79
UniParc:
UPI000006D454,
UPI00003BF714,
UPI00003BF713
EMBL:
AK292084,
AJ279016,
AL139239,
AK001182,
AJ276171,
AJ421515,
AL358938,
BC034245
Ensembl:
ENSG00000095713
KO:
hsa:55118
|
| Nucleutide sequences |
EMBL-CDS:
BAF84773.1,
CAB98267.1,
CAD13394.1,
BAA91540.1,
CAB98269.1,
CAC08451.1,
AAH34245.1,
CAB98268.1
Ensembl_TRS:
ENST00000370597,
ENST00000370591
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000359623,
ENSP00000359629
RefSeq:
NP_060528.3,
NP_001193457.1,
XP_005269995.1,
XP_016871856.1,
XP_016871855.1,
XP_011538219.1
|
| Others |
UniRef100:
UniRef100_Q9NQ79
UniRef90:
UniRef90_Q9NQ79
UniRef50:
UniRef50_Q9NQ79
UniGene:
Hs.500736
CCDS:
CCDS55723.1,
CCDS31266.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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