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55114 ARHGAP17

55114

ARHGAP17

Rho GTPase activating protein 17

protein-coding

Homo sapiens

基因描述

Type Description
Definition Rho GTPase activating protein 17

研究结论

Date Results Publications
2019-03-09 10:44:00 ARHGAP17 functions as a tumor suppressor in cervical cancer that suppresses tumor growth, at least partly, through inhibition of PI3K/AKT signaling and up-regulation of P21 and P27 expression. 30641218
2019-02-23 11:14:00 The bevacizumab-independent VEGF/NRP1/ARHGAP17/Cdc42 regulatory network plays important roles in malignant behavior of breast cancer. 29971782
2018-08-04 11:19:00 In vitro analysis demonstrated that ARHGAP17 overexpression inhibited cell growth and invasion of HCT-8 and HCT-116 cells. 29730655
2016-05-14 11:26:00 show that ARHGAP17 binds to the actin-regulating CIP4 protein in platelets and that Ser-702 phosphorylation interferes with this interaction 26507661
2016-04-02 11:23:00 Rich1 negatively regulates the epithelial cell cycle, proliferation and adhesion by CDC42/RAC1-PAK1-Erk1/2 pathway. 26004135

名称对应

Type IDs
Synonymous MST066, MST110, MSTP038, MSTP066, MSTP110, NADRIN, PP367, PP4534, RICH-1, RICH1, WBP15
Gene
UniProtKB-ID: RHG17_HUMAN
UniprotKB: Q68EM7
UniParc: UPI00000433FD, UPI000006E6B2, UPI0000D619BF, UPI0000F3BE55, UPI0000072047, UPI000004EDFF, UPI0000F3BE54
EMBL: BC001241, AK125358, AJ306731, AF173885, BC080195, AK001170, AJ306732, AL833975, AK027567, AF163257, AK023281, AK291691
Ensembl: ENSG00000140750, ENSG00000288353
KO: hsa:55114
Nucleutide sequences
EMBL-CDS: AAH80195.1, CAD38819.1, AAH01241.1, AAQ13586.1, BAB55203.1, BAF84380.1, CAC37948.1, AAQ13632.1, BAB14506.1, BAC86144.1, CAC37949.1
Gene_ORFName: MSTP110, MSTP066
Ensembl_TRS: ENST00000673560, ENST00000289968, ENST00000303665, ENST00000673196
Protein sequencees
Ensembl_PRO: ENSP00000500849, ENSP00000289968, ENSP00000303130, ENSP00000500372
RefSeq: XP_011544180.1, XP_011544176.1, NP_001006635.1, XP_011544179.1, XP_011544175.1, XP_011544177.1, NP_060524.4, XP_011544178.1, XP_016878879.1, XP_024306104.1
Others
UniRef100: UniRef100_Q68EM7
UniRef90: UniRef90_Q68EM7
UniRef50: UniRef50_Q68EM7
UniGene: Hs.373793
CCDS: CCDS32409.1, CCDS32408.1

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