| Type | Description |
|---|---|
| Definition | protein phosphatase 1 regulatory subunit 8 |
| Date | Results | Publications |
|---|---|---|
| 2019-11-23 11:17:00 | PP1-NIPP1 expression resulted in the build up of RNA-DNA hybrids (R-loops), enhanced chromatin compaction and a diminished repair of DNA double-strand breaks. | 29898919 |
| 2017-03-04 11:59:00 | NIPP1 could be activated by hypoxia and contributed to hypoxia-induced invasive and metastatic potential in hepatocellular carcinoma. | 27644248 |
| 2015-08-01 10:07:00 | Data suggest overexpression of NIPP1 in HeLa cells causes induction of genes of mesenchymal lineage with reduction in cell proliferation; thus, key dephosphorylation events may be involved in epithelial-mesenchymal transition or transdifferentiation. | 25907536 |
| 2013-03-23 11:02:00 | PP1/NIPP1 is a novel molecular compass that controls directed cell migration. | 22815811 |
| 2013-03-23 10:35:00 | The molecular basis by which NIPP1 directs PP1 substrate specificity in the nucleus. | 22940584 |
| Type | IDs |
|---|---|
| Synonymous | ARD-1, ARD1, NIPP-1, NIPP1, PRO2047 |
| Gene |
UniProtKB-ID:
PP1R8_HUMAN,
Q6ICT4_HUMAN
UniprotKB:
Q12972,
Q6ICT4
UniParc:
UPI000002B180,
UPI000002B181,
UPI00001320FD
EMBL:
AF064757,
AF064756,
AF064751,
AF061959,
AK313814,
AF064755,
BC001597,
U14575,
AK292077,
AF061958,
AL109927,
AF064754,
BC013360,
AF064752,
AF064753,
AK297771,
CH471059,
AF126488,
CR450309,
AL020997
Ensembl:
ENSG00000117751
KO:
hsa:5511
|
| Nucleutide sequences |
EMBL-CDS:
EAX07732.1,
AAD31542.1,
AAD24669.1,
BAF84766.1,
AAD31541.1,
AAH01597.1,
AAH13360.1,
AAA64749.1,
AAD24670.1,
AAD22486.1,
EAX07731.1,
EAX07736.1,
BAG60117.1,
CAG29305.1,
BAG36550.1
Gene_ORFName:
hCG_2032356
Ensembl_TRS:
ENST00000373931,
ENST00000236412,
ENST00000311772
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000236412,
ENSP00000363042,
ENSP00000311677
RefSeq:
NP_612568.1,
XP_016857083.1,
NP_002704.1,
NP_054829.2
|
| Others |
UniRef100:
UniRef100_Q12972-2,
UniRef100_Q12972
UniRef90:
UniRef90_Q12972-2,
UniRef90_Q12972
UniRef50:
UniRef50_Q12972,
UniRef50_Q12972-2
UniGene:
Hs.533474
CCDS:
CCDS311.1,
CCDS312.1,
CCDS313.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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