| Type | Description |
|---|---|
| Definition | schlafen family member 12 |
| Date | Results | Publications |
|---|---|---|
| 2020-04-18 12:37:00 | HSLFN12's partner hSerpinB12 may contribute to heterochromatin formation. | 31026779 |
| 2020-02-01 11:40:00 | The SLFN12 protein and an apoptosis activation marker were co-localized in syncytiotrophoblast of human placentas, where levels of estrogen-related hormones are high, and dynamic cell turnover by apoptosis is critical for successful implantation and placenta development. | 31420216 |
| 2019-12-28 12:44:00 | SLFN12 overexpression reduced MDA-MB-231 mammosphere formation. SLFN12 overexpression decreased ZEB1 and Slug protein despite increased ZEB1 and Slug mRNA . SLFN12 knockdown increased ZEB1 protein. Co-expressing ZEB1 attenuated the SLFN12 effect on E-cadherin mRNA and proliferation. | 31838790 |
| 2019-10-19 10:24:00 | Schlafen 12 (SLFN12) is a cytosolic protein that stimulates sucrase-isomaltase (SI) expression. | 30875077 |
| 2018-09-15 11:25:00 | SLFN12 regulates human enterocytic differentiation by a pathway involving SERPB12, the deubiquitylases, and Cdx2. | 30045019 |
| Type | IDs |
|---|---|
| Synonymous | SLFN3 |
| Gene |
UniProtKB-ID:
SLN12_HUMAN
UniprotKB:
Q8IYM2
UniParc:
UPI000013E9E5
EMBL:
BC035605,
AK001122,
AK291826
Ensembl:
ENSG00000172123
KO:
hsa:55106
|
| Nucleutide sequences |
EMBL-CDS:
BAF84515.1,
BAA91512.1,
AAH35605.1
Ensembl_TRS:
ENST00000452764,
ENST00000394562,
ENST00000304905
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000378063,
ENSP00000302077,
ENSP00000394903
RefSeq:
XP_011523269.1,
XP_016880298.1,
NP_001275938.1,
XP_005258052.1,
XP_016880299.1,
NP_060512.3,
XP_016880300.1,
XP_024306590.1
|
| Others |
UniRef100:
UniRef100_Q8IYM2
UniRef90:
UniRef90_Q8IYM2
UniRef50:
UniRef50_Q8IYM2
UniGene:
Hs.663548
CCDS:
CCDS11295.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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