| Type | Description |
|---|---|
| Definition | Ral GEF with PH domain and SH3 binding motif 2 |
| Date | Results | Publications |
|---|---|---|
| 2018-10-06 12:02:00 | In fact the overexpression of RalGPS2 or of its PH-domain increased markedly the number and the length of nanotubes, while the knock-down of RalGPS2 caused a strong reduction of these structures. Moreover, using a series of RalA mutants impaired in the interaction with different downstream components (Sec5, Exo84, RalBP1) we demonstrated that the interaction of RalA with Sec5 is required for TNTs formation | 29208460 |
| 2017-07-15 12:10:00 | RALGPS2 is implicated in the control of cell cycle progression and survival in the in vitro growth of NSCLC cell lines. This function is largely independent of Ral GTPases and associated with modulation of Skp2, p27 and p21 cell cycle regulators | 27149377 |
| Type | IDs |
|---|---|
| Synonymous | dJ595C2.1 |
| Gene |
UniProtKB-ID:
RGPS2_HUMAN
UniprotKB:
Q86X27
UniParc:
UPI000000DBE1,
UPI00000720F8,
UPI000004A0CB
EMBL:
AL162255,
CH471067,
AK001106,
AK301753,
AL355520,
BC047391
Ensembl:
ENSG00000116191
KO:
hsa:55103
|
| Nucleutide sequences |
EMBL-CDS:
BAA91506.1,
AAH47391.1,
EAW91029.1,
EAW91028.1,
BAH13547.1
Ensembl_TRS:
ENST00000367635,
ENST00000367634
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000356607,
ENSP00000356606
RefSeq:
XP_016857080.1,
XP_006711473.1,
XP_011507990.1,
NP_001273176.1,
NP_689876.2,
XP_006711474.1
|
| Others |
UniRef100:
UniRef100_Q86X27
UniRef90:
UniRef90_Q9ERD6
UniRef50:
UniRef50_Q9ERD6
UniGene:
Hs.632485
CCDS:
CCDS65733.1,
CCDS1325.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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