| Type | Description |
|---|---|
| Definition | RPA1 related single stranded DNA binding protein, X-linked |
| Date | Results | Publications |
|---|---|---|
| 2021-03-20 13:35:00 | RADX controls RAD51 filament dynamics to regulate replication fork stability. | 33453169 |
| 2019-12-07 10:09:00 | RADX buffers RAD51 to ensure the right amount of reversal and protection to maintain genome stability. | 30021152 |
| 2018-07-21 10:28:00 | RADX interacts with single-stranded DNA to promote replication fork stability. | 29021206 |
| 2017-09-30 13:57:00 | By antagonizing RAD51 at forks, RADX allows cells to maintain a high capacity for homology-directed repair while ensuring that replication functions of RAD51 are properly regulated. Thus, RADX is essential to achieve the proper balance of RAD51 activity to maintain genome stability. | 28735897 |
| Type | IDs |
|---|---|
| Synonymous | CXorf57 |
| Gene |
UniProtKB-ID:
RADX_HUMAN
UniprotKB:
Q6NSI4
UniParc:
UPI000021220A,
UPI000013FDA6,
UPI0000212207,
UPI0002A7BC52
EMBL:
AL590808,
CH471120,
AK001040,
BC011483,
BC070110,
BC054032,
BC033709,
AL606833,
AK024253
Ensembl:
ENSG00000147231
KO:
hsa:55086
|
| Nucleutide sequences |
EMBL-CDS:
EAX02740.1,
AAH33709.1,
AAH11483.1,
BAB14859.1,
AAH54032.1,
AAH70110.1
Ensembl_TRS:
ENST00000372548,
ENST00000461251,
ENST00000372544
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000361623,
ENSP00000361628,
ENSP00000432238
RefSeq:
NP_001171711.1,
NP_060485.4
|
| Others |
UniRef100:
UniRef100_Q6NSI4
UniRef90:
UniRef90_Q6NSI4
UniRef50:
UniRef50_Q6NSI4
UniGene:
Hs.274267
CCDS:
CCDS14519.1,
CCDS55470.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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