| Type | Description |
|---|---|
| Definition | TAP binding protein like |
| Date | Results | Publications |
|---|---|---|
| 2020-09-26 13:04:00 | Distinct Polymorphisms in HLA Class I Molecules Govern Their Susceptibility to Peptide Editing by TAPBPR. | 31693900 |
| 2020-01-25 12:25:00 | The ability of TAPBPR to interact with MHC class I molecules outside of the ER. | 30077416 |
| 2019-05-11 10:18:00 | The results demonstrate an inverse relationship between MHC-I peptide occupancy and TAPBPR binding affinity, wherein the lifetime and structural features of transiently bound peptides control the regulation of a conformational switch located near the TAPBPR binding site, which triggers TAPBPR release. | 29988068 |
| 2019-04-27 10:55:00 | Data suggest therapeutic potential of TAP binding protein like tapasin-related protein (TAPBPR) manipulation to increase tumour immunogenicity. | 30484775 |
| 2018-10-20 10:32:00 | soluble TAPBPR, consisting of the luminal domain alone, added to intact cells, also functions as an effective peptide editor on surface MHC I molecules. | 30213851 |
| Type | IDs |
|---|---|
| Synonymous | TAPBP-R, TAPBPR |
| Gene |
UniProtKB-ID:
TPSNR_HUMAN
UniprotKB:
Q9BX59
UniParc:
UPI0005093981,
UPI0005093986,
UPI0005093978,
UPI0005093982,
UPI0005093977,
UPI000013D6F6,
UPI000387BEF7
EMBL:
BC015017,
AK002056,
AC005840,
AK001005
Ensembl:
ENSG00000139192
KO:
hsa:55080
|
| Nucleutide sequences |
EMBL-CDS:
BAA91465.1,
BAB41077.1,
AAH15017.1
Ensembl_TRS:
ENST00000266556
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000266556
RefSeq:
XP_005253757.1,
NP_001338284.1,
XP_016875035.1,
XP_016875034.1,
NP_060479.3
|
| Others |
UniRef100:
UniRef100_Q9BX59
UniRef90:
UniRef90_Q9BX59
UniRef50:
UniRef50_Q9BX59
UniGene:
Hs.504597
CCDS:
CCDS8546.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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