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55074 OXR1

55074

OXR1

oxidation resistance 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition oxidation resistance 1

研究结论

Date Results Publications
2020-10-10 12:57:00 Oxidation resistance 1 prevents genome instability through maintenance of G2/M arrest in gamma-ray-irradiated cells. 31845986
2020-05-30 11:47:00 Over-expression of Oxr1 was able to delay neuromuscular abnormalities in the hSOD1G93A amyotrophic lateral sclerosis mouse model. 31642482
2020-04-04 11:39:00 Loss of OXR1 is Associated with an Autosomal-Recessive Neurological Disease with Cerebellar Atrophy and Lysosomal Dysfunction. 31785787
2019-12-21 10:26:00 Low OXR1 expression is associated with the development of esophageal squamous cell carcinoma. 30852977
2019-10-12 12:31:00 findings provide new insights into the mechanism by which senescent cells are highly resistant to oxidative stress and suggest that OXR1 is a novel senolytic target that can be further exploited for the development of new senolytic agents 29766639

名称对应

Type IDs
Synonymous Nbla00307, TLDC3
Gene
UniProtKB-ID: OXR1_HUMAN
UniprotKB: Q8N573
UniParc: UPI0001C305EA, UPI0000375268, UPI000013F250, UPI00017994EE, UPI0000210466, UPI0000210462, UPI00004A2871, UPI0001914BEA
EMBL: AK127563, DQ020202, AP002090, AC023344, FN650109, BC032710, AK124441, AP000430, AK292899, AK296561, AK000987, AL833193, AB075503, AK096148, AC090579, AK316153, AK303695, AF309387, AC027031, FN650108
Ensembl: ENSG00000164830
KO: hsa:55074
Nucleutide sequences
EMBL-CDS: BAG54523.1, CBI84065.1, CAI46186.1, BAF85588.1, AAH32710.1, CBI84064.1, BAA91456.1, BAE45753.1, BAH14524.1, BAH12388.1, BAC85852.1, BAH14021.1, AAY26396.1, BAC04711.1, AAG25715.1
Gene_ORFName: Nbla00307
Ensembl_TRS: ENST00000312046, ENST00000497705, ENST00000297447, ENST00000449762, ENST00000517566, ENST00000531443, ENST00000442977
Protein sequencees
Ensembl_PRO: ENSP00000431966, ENSP00000405424, ENSP00000408659, ENSP00000297447, ENSP00000429205, ENSP00000311026, ENSP00000431014
RefSeq: XP_016869078.1, XP_016869080.1, NP_060472.2, XP_016869084.1, XP_016869082.1, XP_016869086.1, XP_016869079.1, XP_016869089.1, XP_016869083.1, NP_001185463.1, NP_851999.2, NP_001185464.1, XP_016869088.1, XP_006716658.1, NP_001185461.1, XP_016869081.1, XP_016869087.1, XP_016869085.1, NP_001185462.1
Others
UniRef100: UniRef100_Q8N573
UniRef90: UniRef90_Q8N573
UniRef50: UniRef50_Q4KMM3
UniGene: Hs.127286, Hs.701892
CCDS: CCDS56548.1, CCDS47909.1, CCDS56547.1, CCDS6304.2, CCDS56550.1, CCDS56549.1

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