| Type | Description |
|---|---|
| Definition | protein phosphatase 1 regulatory subunit 3C |
| Date | Results | Publications |
|---|---|---|
| 2016-02-27 11:15:00 | PPP1R3C, a novel hypermethylated gene in colorectal cancer, may play a critical role in cancer cell growth in association with glucose levels. | 25846879 |
| 2015-07-04 12:58:00 | detection of methylation of PPP1R3C alone or in combination with EFHD1 in plasma DNA showed high sensitivity and specificity in CRC detection, and may be useful detection method for CRC, especially for early-stage CRCs. | 24861485 |
| 2011-12-03 11:22:00 | Findings suggest that variations in PTG may condition the course of Lafora disease and establish PTG as a potential target for pharmacogenetic and therapeutic approaches. | 21738631 |
| 2010-11-27 10:45:00 | Results demonstrated that HIF1 promotes glycogen accumulation through regulating PPP1R3C expression under hypoxia, which revealed a novel metabolic adaptation of cells to hypoxia. | 20888814 |
| 2010-01-21 00:00:00 | phosphorylation of R5/PTG at Ser-8 by AMPK accelerates its laforin/malin-dependent ubiquitination and subsequent proteasomal degradation, which results in a decrease of its glycogenic activity. | 19171932 |
| Type | IDs |
|---|---|
| Synonymous | PPP1R5, PTG |
| Gene |
UniProtKB-ID:
PPR3C_HUMAN
UniprotKB:
Q9UQK1
UniParc:
UPI000006EFF1
EMBL:
AF110824,
BX537399,
Y18207,
BC012625,
AK313149,
AL359986,
CH471066
Ensembl:
ENSG00000119938
KO:
hsa:5507
|
| Nucleutide sequences |
EMBL-CDS:
AAD33215.1,
CAD97641.1,
BAG35967.1,
EAW50107.1,
CAA77082.1,
AAH12625.1
Ensembl_TRS:
ENST00000238994
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000238994
RefSeq:
NP_005389.1
|
| Others |
UniRef100:
UniRef100_Q9UQK1
UniRef90:
UniRef90_Q9UQK1
UniRef50:
UniRef50_Q9UQK1
UniGene:
Hs.303090,
Hs.744999
CCDS:
CCDS7416.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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