| Type | Description |
|---|---|
| Definition | NRDE-2, necessary for RNA interference, domain containing |
| Date | Results | Publications |
|---|---|---|
| 2019-07-06 12:41:00 | NRDE2 interacts with MTR4's key residues, locks MTR4 in a closed conformation, and inhibits MTR4 interaction with the exosome as well as proteins important for MTR4 recruitment | 30842217 |
| 2019-03-30 13:11:00 | Our work establishes a conserved role for human NRDE2 in RNA splicing, characterizes the severe genomic instability phenotypes observed upon loss of NRDE2, and highlights the direct regulation of CEP131 splicing as one of multiple mechanisms through which such phenotypes might be explained. | 30538148 |
| 2018-12-22 11:22:00 | this study found that Mtr4 association with the human homolog of fission yeast Nrl1, NRDE-2, defines a novel function for Mtr4 in the DNA damage response pathway. | 29902117 |
| Type | IDs |
|---|---|
| Synonymous | C14orf102 |
| Gene |
UniProtKB-ID:
NRDE2_HUMAN
UniprotKB:
Q9H7Z3
UniParc:
UPI00001FD9DB
EMBL:
AK024113,
AL161662,
BC098568,
AK000870,
AK294958
Ensembl:
ENSG00000119720
KO:
hsa:55051
|
| Nucleutide sequences |
EMBL-CDS:
BAA91404.1,
BAG58032.1,
BAB14830.1,
AAH98568.1
Ensembl_TRS:
ENST00000354366
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000346335
RefSeq:
XP_016876885.1,
XP_016876884.1,
XP_016876883.1,
XP_011535188.1,
NP_060440.2
|
| Others |
UniRef100:
UniRef100_Q9H7Z3
UniRef90:
UniRef90_Q9H7Z3
UniRef50:
UniRef50_Q9H7Z3
UniGene:
Hs.528131
CCDS:
CCDS9890.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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