| Type | Description |
|---|---|
| Definition | FKBP prolyl isomerase 14 |
| Date | Results | Publications |
|---|---|---|
| 2020-11-21 13:16:00 | The novel missense mutation Met48Lys in FKBP22 changes its structure and functions. | 31949249 |
| 2020-02-08 11:17:00 | This patient points out the existence of a wider phenotypic spectrum of FKBP14-kEDS to include early onset muscle disease. | 30561154 |
| 2018-05-19 11:27:00 | FKBP14 may act as an oncogene through suppressing apoptosis and promoting motility in human cervical carcinogenesis. | 28731139 |
| 2018-02-10 10:43:00 | Genetic studies showed that the patient harboured a homozygous mutation (c.362dupC p.Glu122Argfs*7) in the FKBP14 gene, confirming kyphoscoliotic EDS related to this gene. | 27905128 |
| 2018-01-13 12:53:00 | FKBP14 may act as an oncogene in osteosarcoma via suppressing apoptosis and promoting invasion and adhesion in osteosarcoma carcinogenesis | 27223089 |
| Type | IDs |
|---|---|
| Synonymous | EDSKMH, EDSKSCL2, FKBP22, IPBP12 |
| Gene |
UniProtKB-ID:
FKB14_HUMAN,
A0A090N7V8_HUMAN
UniprotKB:
Q9NWM8,
A0A090N7V8
UniParc:
UPI0000035974
EMBL:
BC005206,
CH471073,
AK000738,
AACC02000087,
AY358643
Ensembl:
ENSG00000106080
KO:
hsa:55033
|
| Nucleutide sequences |
EMBL-CDS:
AAQ89006.1,
AAH05206.1,
BAA91351.1,
EAW93929.1,
EAL24457.1
Gene_ORFName:
UNQ322/PRO381,
tcag7.681,
hCG_38314
Ensembl_TRS:
ENST00000222803
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000222803
RefSeq:
NP_060416.1
|
| Others |
UniRef100:
UniRef100_Q9NWM8
UniRef90:
UniRef90_Q9NWM8
UniRef50:
UniRef50_Q9NWM8
UniGene:
Hs.390838
CCDS:
CCDS5423.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员