| Type | Description |
|---|---|
| Definition | ubiquitin specific peptidase 47 |
| Date | Results | Publications |
|---|---|---|
| 2021-01-16 16:01:00 | Targeting USP47 overcomes tyrosine kinase inhibitor resistance and eradicates leukemia stem/progenitor cells in chronic myelogenous leukemia. | 33397955 |
| 2020-12-05 12:57:00 | USP47-mediated deubiquitination and stabilization of YAP contributes to the progression of colorectal cancer. | 31748975 |
| 2020-01-04 10:50:00 | lncRNA LINC00668 acted as an oncogenic role in CRC cells by sponging miR-188-5p and upregulating USP47 | 31233752 |
| 2019-07-13 10:11:00 | These results demonstrate, for the first time, the role for USP47, as a novel target of Sox9, in the regulation of epithelial-mesenchymal transition and metastasis of colorectal cancer cells. | 29162839 |
| 2019-06-08 13:24:00 | these data reveal a new post-transcriptional role for USP47 and USP7 in inflammation by regulating inflammasome activation and the release of the pro-inflammatory cytokines IL-1beta and IL-18, and implicate dual USP7 and USP47 inhibitors as potential therapeutic agents for inflammatory disease. | 30206189 |
| Type | IDs |
|---|---|
| Synonymous | TRFP |
| Gene |
UniProtKB-ID:
UBP47_HUMAN,
Q68D97_HUMAN
UniprotKB:
Q96K76,
Q68D97
UniParc:
UPI00001F9D69,
UPI0001E88E94,
UPI00004DC7F5,
UPI000041A141,
UPI00001AA24E
EMBL:
AL832991,
AK027362,
BC071559,
BC047044,
AK092290,
AC124276,
AC104383,
AK127264,
AK000734,
CR749502,
BC000226,
AK074076
Ensembl:
ENSG00000170242
KO:
hsa:55031
|
| Nucleutide sequences |
EMBL-CDS:
BAG54467.1,
BAB55063.1,
BAB84902.1,
CAH56337.1,
BAA91348.1,
AAH47044.2,
AAH00226.2,
CAH18323.1
Ensembl_TRS:
ENST00000399455,
ENST00000527733,
ENST00000339865
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000382382,
ENSP00000339957,
ENSP00000433146
RefSeq:
XP_016873443.1,
NP_001359030.1,
NP_001269588.1,
NP_001359025.1,
XP_011518498.1,
NP_001359023.1,
NP_001359031.1,
NP_001359028.1,
NP_001359021.1,
NP_001359026.1,
NP_001359024.1,
NP_001359029.1,
NP_060414.3,
NP_001359032.1,
NP_001359022.1,
NP_001359020.1,
NP_001359027.1,
NP_001317137.1
|
| Others |
UniRef100:
UniRef100_Q68D97,
UniRef100_Q96K76
UniRef90:
UniRef90_Q68D97,
UniRef90_Q96K76
UniRef50:
UniRef50_Q96K76,
UniRef50_Q68D97
UniGene:
Hs.577256
CCDS:
CCDS41619.1,
CCDS81554.1,
CCDS60725.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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