| Type | Description |
|---|---|
| Definition | B cell scaffold protein with ankyrin repeats 1 |
| Date | Results | Publications |
|---|---|---|
| 2019-12-28 11:37:00 | This is the first study showing an association of BLK rs2736340T/C and rs13277113A/G and BANK1 R61H with susceptibility to SLE in a Latin-American population. In addition, some BLK and BANK1 interactions were associated with susceptibility to SLE. | 31134304 |
| 2019-06-08 12:54:00 | Study demonstrates the functional consequences of rare and low frequency missense variants in the interacting proteins BLK and BANK1, which are present alone, or in combination, in a substantial proportion of lupus patients. The rare variants found in patients, but not those found exclusively in controls, impair suppression of IRF5 and type-I IFN in human B cell lines. | 31101814 |
| 2019-06-01 12:28:00 | This study was the first to demonstrate that a BANK1 gene SNP (rs3733197) could confer genetic predisposition in polymyositis/dermatomyositis (PM/DM) patients and PM/DM patients with ILD in a Chinese Han population. | 30145638 |
| 2018-12-22 10:22:00 | Our data defines a minimal set of risk associated eQTLs predicted to be involved in the expression of BANK1 modulated through epigenetic regulation and splicing. These findings allow us to suggest that the increased expression of BANK1 will have an impact on B-cell mediated disease pathways. | 30096841 |
| 2018-06-09 11:20:00 | our results indicated that the BLK rs13277113 polymorphism was involved in the genetic background of RA in Chinese population and the association of BANK1 rs3733197 polymorphism with RA was dependent on the genotype of BLK rs13277113 polymorphism, highlighting B-cell response implicated in the pathogenesis of RA. | 28925718 |
| Type | IDs |
|---|---|
| Synonymous | BANK |
| Gene |
UniProtKB-ID:
BANK1_HUMAN
UniprotKB:
Q8NDB2
UniParc:
UPI000020B253,
UPI0000E090D7,
UPI000020B24F,
UPI0000D6159D
EMBL:
AL834291,
AB063170,
BC032241,
AK091523,
AC095062,
AK000713,
EU051376,
AC109928,
AC093694,
AP002075,
AK292133
Ensembl:
ENSG00000153064
KO:
hsa:55024
|
| Nucleutide sequences |
EMBL-CDS:
BAA91337.1,
AAH32241.2,
BAF84822.1,
ABW74340.1,
BAC03685.1,
BAB79255.1,
CAD38965.2
Ensembl_TRS:
ENST00000428908,
ENST00000322953,
ENST00000508653,
ENST00000444316,
ENST00000504592
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000412748,
ENSP00000388817,
ENSP00000320509,
ENSP00000422314,
ENSP00000421443
RefSeq:
NP_001120979.3,
NP_060405.5,
NP_001077376.3,
XP_016863826.1
|
| Others |
UniRef100:
UniRef100_Q8NDB2
UniRef90:
UniRef90_Q8NDB2
UniRef50:
UniRef50_Q8NDB2
UniGene:
Hs.480400
CCDS:
CCDS47116.1,
CCDS34038.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员