| Type | Description |
|---|---|
| Definition | protein phosphatase 1 regulatory inhibitor subunit 1A |
| Date | Results | Publications |
|---|---|---|
| 2020-04-11 12:45:00 | HOXC-AS3 is aberrantly overexpressed in breast cancers especially the HER2+ type. High expression of HOXC-AS3 has a relationship with poor clinical outcomes of breast cancer. HOXC-AS3 regulates cell invasion and migration both in vitro and in vivo. Results demonstrated that miR-3922-5p was a direct target of HOXC-AS3, and PPP1R1A was a target of miR-3922-5p in breast cancer. | 31797701 |
| 2019-03-16 12:20:00 | High PPP1R1A expression is associated with ewing sarcoma tumorigenesis and metastasis. | 29059150 |
| 2016-10-01 12:33:00 | These findings suggest that the human G109E inhibitor-1 variant impairs sarcoplasmic reticulum Ca-cycling and promotes arrhythmogenesis under stress conditions. | 26455482 |
| 2014-04-26 10:04:00 | I-1 and sarco/endoplasmic reticulum Ca2+ -ATPase synergistically induce the vascular smooth muscle cell contractile phenotype. | 24249716 |
| 2010-09-15 22:06:00 | Observational study of gene-disease association. (HuGE Navigator) | 19913121 |
| Type | IDs |
|---|---|
| Synonymous | I1, IPP1 |
| Gene |
UniProtKB-ID:
PPR1A_HUMAN
UniprotKB:
Q13522
UniParc:
UPI0000229454
EMBL:
U48707,
AY063766,
BC022470,
CR457003
Ensembl:
ENSG00000135447
KO:
hsa:5502
|
| Nucleutide sequences |
EMBL-CDS:
CAG33284.1,
AAB02402.1,
AAH22470.1,
AAL48321.1
Ensembl_TRS:
ENST00000257905
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000257905
RefSeq:
NP_006732.3,
XP_005269052.1,
XP_006719534.1
|
| Others |
UniRef100:
UniRef100_Q13522
UniRef90:
UniRef90_Q13522
UniRef50:
UniRef50_Q13522
UniGene:
Hs.505662
CCDS:
CCDS44912.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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