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55014 STX17

55014

STX17

syntaxin 17

protein-coding

Homo sapiens

基因描述

Type Description
Definition syntaxin 17

研究结论

Date Results Publications
2020-10-24 14:11:00 Decoding three distinct states of the Syntaxin17 SNARE motif in mediating autophagosome-lysosome fusion. 32817423
2020-06-13 10:47:00 EACC affects the translocation of SNAREs Stx17 and SNAP29 on autophagosomes without impeding the completion of autophagosomes. EACC treatment also reduces the interaction of Stx17 with the HOPS subunit VPS33A and the cognate lysosomal R-SNARE VAMP8. 31188703
2019-11-09 11:46:00 Stx17 knockout diminished LC3 response and reduced sequestration of the prototypical bulk autophagy cargo lactate dehydrogenase. We conclude that Stx17 is a TBK1 substrate and that together they orchestrate assembly of mammalian pre-autophagosomal structure 30827897
2019-10-05 11:03:00 results reveal that the Stx17-PGAM5 axis plays pivotal roles in mitochondrial division and PINK1/Parkin-mediated mitophagy. 30237312
2019-09-14 12:00:00 The cytotoxicity of coxsackievirus B3 is associated with a blockage of autophagic flux mediated by reduced STX17 expression. 29445155

名称对应

Type IDs
Gene
UniProtKB-ID: STX17_HUMAN
UniprotKB: P56962
UniParc: UPI000013D04E
EMBL: CH471105, AL358937, BC101566, AK000658, BC101564
Ensembl: ENSG00000136874
KO: hsa:55014
Nucleutide sequences
EMBL-CDS: AAI01565.1, AAI01567.1, BAA91311.1, EAW58920.1
Ensembl_TRS: ENST00000525640, ENST00000259400, ENST00000534052
Protein sequencees
Ensembl_PRO: ENSP00000433484, ENSP00000259400, ENSP00000435981
RefSeq: XP_011517125.1, NP_060389.2, XP_011517123.1, XP_024303361.1, XP_016870364.1, XP_011517122.1
Others
UniRef100: UniRef100_P56962
UniRef90: UniRef90_P56962
UniRef50: UniRef50_P56962
UniGene: Hs.704031
CCDS: CCDS6745.1

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