HERC6 - HECT and RLD domain containing E3 ubiquitin protein ligase family member 6-BMKCloudï½ç¾è¿å®¢äº

例如："NBL1", "4681", "drought"

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55008 HERC6

基因描述

Type	Description
Definition	HECT and RLD domain containing E3 ubiquitin protein ligase family member 6

研究结论

Date	Results	Publications
2010-01-21 00:00:00	HERC6 ancestor emerged in nematodes and that the family expanded throughout evolution. The mRNA expression pattern was found to be diverse in selected tissues and cells	15676274

名称对应

Type	IDs
Gene	UniProtKB-ID: HERC6_HUMAN UniprotKB: Q8IVU3 UniParc: UPI00004C6F59, UPI00004C7A84, UPI0000F0A543 EMBL: AF336798, BC042047, AK092403, AK000644, AL833664, AK295832, BC035775, BX647121, AY653201 Ensembl: ENSG00000138642 KO: hsa:55008
Nucleutide sequences	EMBL-CDS: AAH42047.2, AAH35775.2, BAG58647.1, BAC03879.1, AAV66895.1, AAQ14893.1, BAA91303.1, CAI46151.1, CAI46056.1 Ensembl_TRS: ENST00000264346, ENST00000380265
Protein sequencees	Ensembl_PRO: ENSP00000369617, ENSP00000264346 RefSeq: XP_011530355.1, XP_005263140.1, NP_060382.3, NP_001158608.1, XP_016863822.1
Others	UniRef100: UniRef100_Q8IVU3 UniRef90: UniRef90_Q8IVU3 UniRef50: UniRef50_Q8IVU3 UniGene: Hs.529317 CCDS: CCDS47098.1, CCDS54777.1

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mRNA

Protein

UniprotKB

Description

Refseq

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26949039	System-Wide Modulation of HECT E3 Ligases with Selective Ubiquitin Variant Probes. Mol Cell Wei Zhang , Kuen-Phon Wu , Maria A Sartori , Hari B Kamadurai , Alban Ordureau , Chong Jiang , Peter Y Mercredi , Ryan Murchie , Jicheng Hu , Avinash Persaud , Manjeet Mukherjee , Nan Li , Anne Doye , John R Walker , Yi Sheng , Zhenyue Hao , Yanjun Li , Kevin R Brown , Emmanuel Lemichez , Junjie Chen , Yufeng Tong , J Wade Harper , Jason Moffat , Daniela Rotin , Brenda A Schulman , Sachdev S Sidhu	2016-04-07	-
25192599	Interaction of amyotrophic lateral sclerosis/frontotemporal lobar degeneration-associated fused-in-sarcoma with proteins involved in metabolic and protein degradation pathways. Neurobiol. Aging Tao Wang , Xin Jiang , Gang Chen , Jin Xu	2015-01-01	Fus, Sfpq, CDH4, SAE1, ABCF2, SF3B4, SF3A1, TUBA1B, SYNCRIP, CCT7, CCT4, CCT2, PAICS, CCT8, CFL1, SF3A3, CKAP4, YWHAQ, NUDT21, CPSF6, ATXN2L, DDX42, CKB, HIST4H4, LSM12, RAVER1, KLHL40, PM20D2, CSE1L, AMOT, GIMAP8, DGKA, DDX1, DDX5, DHX15, DLD, AHCY, EEF1A1, ABCA1, EEF1G, EEF2, EIF4A1, CEP112, ENO1, ADCK5, TUBB, ALB, F7, FASN, ALDOA, CCT5, NCOA6, ERP44, UFL1, HARS2, SF3B3, FUS, RAD54B, FAM98A, GAPDH, SERBP1, PHGDH, ERAL1, GOLIM4, GLUD1, GNAS, GOT2, GPI, IGKV1-5, SLC25A5, PDIA3, GSTP1, YPEL1, H3F3A, H3F3B, ANXA2P2, ANXA5, ACACA, HNRNPD, HNRNPF, HNRNPH1, HNRNPK, HNRNPL, HNRNPU, HPRT1, PRMT1, HSPA5, HSPA8, HSPA9, HSP90AA1, HSP90AB1, HSPD1, LRRIQ4, GEN1, ITK, KPNB1, KPNA2, LDHA, LDHB
22939624	Quantitative analysis of HSP90-client interactions reveals principles of substrate recognition. Cell Mikko Taipale , Irina Krykbaeva , Martina Koeva , Can Kayatekin , Kenneth D Westover , Georgios I Karras , Susan Lindquist	2012-08-31	NR1H3, TRIM10, SGK2, PREB, CDK3, TNK2, CDK4, CDK6, CDK7, CDK9, LOC400927-CSNK1E, PCGF3, TESK2, MERTK, KAT5, CEBPE, NPRL2, CAMKK2, MAP3K2, FASTK, RCBTB2, PIM2, WWP1, CHEK1, CDC37, MAP4K1, IRAK3, TP53RK, STK38, KLHL32, KLHL29, FBXO17, CLK2, CLK3, FBXO27, ASB17, RNF19B, ACVR1C, GRK7, MAP3K8, ASB6, MYO3B, RAB40A, CSF1R, FBXL14, CSNK1A1, CSNK1E, HIPK4, PDIK1L, KLHL23, SH3RF2, SGK223, DAPK3, DCLK2, ZBTB49, DLX6, DMPK, EGFR, EPHA2, EPHA1, EPHA4, EPHB1, EPHB6, ERBB2, ERBB3, ERBB4, AKT2, ESR1, PTK2B, FBXL13, FER, FES, MAPK15, FGFR1, FGFR3, FGR, ICK, TRIM32, TCF25, STK38L, FOXM1, MAST2, PASK, LARP4B, FBXO28, DTX4, FLT4, ZC3H7B, FBXW11, TRIM2, SF3B3, TSSK2, SGK3, ALK, FRK, ABL1, FYN, KLHL34, FBXL2
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