| Type | Description |
|---|---|
| Definition | protein phosphatase 1 catalytic subunit beta |
| Date | Results | Publications |
|---|---|---|
| 2021-04-03 13:30:00 | Integrative genomics analysis of eQTL and GWAS summary data identifies PPP1CB as a novel bone mineral density risk genes. | 32266926 |
| 2020-04-04 12:51:00 | The association of MYPT1 with PP1cbeta was profoundly reduced in the presence of excess TIMAP, leading to proteasomal MYPT1 degradation. | 31315927 |
| 2020-01-18 12:04:00 | our experiments support that PPP1CB and KPC2 together inhibit the activity of HOXA2 by activating its nuclear export, but favored HOXA2 de-ubiquitination and stabilization thereby establishing a store of HOXA2 in the cytoplasm. | 31323436 |
| 2019-02-16 12:29:00 | PPP1CB mutation is associated with Noonan syndrome. | 30368668 |
| 2017-10-21 12:14:00 | This report gives further support that this novel RASopathy-PPP1CB-related Noonan syndrome with loose anagen hair-shares great similarity to Noonan syndrome-like disorder with loose anagen hair, and expands the phenotypic spectrum by adding the cranial vault abnormality. | 28211982 |
| Type | IDs |
|---|---|
| Synonymous | HEL-S-80p, NSLH2, PP-1B, PP1B, PP1beta, PPP1CD |
| Gene |
UniProtKB-ID:
PP1B_HUMAN,
V9HW04_HUMAN
UniprotKB:
P62140,
V9HW04
UniParc:
UPI000000007B
EMBL:
AF092905,
EU668339,
U10999,
CR542285,
AC097724,
X80910,
U11003,
BX647970,
U10998,
BC002697,
CR542263,
U11001,
U11000,
BC012045,
CH471053,
U11002,
AK312329,
BT019744,
U11005,
U11004
Ensembl:
ENSG00000213639
KO:
hsa:5500
|
| Nucleutide sequences |
EMBL-CDS:
AAV38549.1,
BAG35251.1,
CAG47059.1,
AAF01137.1,
AAY24124.1,
EAX00528.1,
CAG47080.1,
EAX00530.1,
AAA85093.1,
AAH12045.1,
CAA56870.1,
EAX00529.1,
AAH02697.1,
EAX00527.1,
ACF94492.1
Ensembl_TRS:
ENST00000296122,
ENST00000395366,
ENST00000358506
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000378769,
ENSP00000296122,
ENSP00000351298
RefSeq:
NP_996759.1,
NP_002700.1
|
| Others |
UniRef100:
UniRef100_P62140
UniRef90:
UniRef90_P62140
UniRef50:
UniRef50_P62140
UniGene:
Hs.702907
CCDS:
CCDS33169.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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