Type | Description |
---|---|
Definition | protoporphyrinogen oxidase |
Date | Results | Publications |
---|---|---|
2020-12-26 13:11:00 | Two new mutations in the PPOX gene in a patient with variegate porphyria. | 32247286 |
2020-07-04 11:40:00 | Mount Sinai Porphyrias Diagnostic Laboratory diagnosed 54 unrelated Variegate Porphyria individuals with 20 PPOX novel mutations. | 30385147 |
2019-06-01 10:21:00 | The genetic test showed a heterozygous mutation in the gene encoding Protoporphyrinogen Oxidase (PPOX); c.2T > A (p.Met1Lys) on chromosome 1q23, which supports the diagnosis of Variegate Porphyria | 29550908 |
2018-01-13 10:05:00 | the regulation of PPOX gene expression can also occur through a post-transcriptional modulation of the amount of gene product and this modulation can be mediated by 5' untranslated exon 1. | 27667166 |
2016-06-28 11:15:00 | GAPDH and protoporphyrinogen oxidase were shown to have higher expression in faster growing cell lines and primary tumors. Pharmacologic inhibition of GAPDH or PPOX reduced the growth of colon cancer cells in vitro | 25944804 |
Type | IDs |
---|---|
Synonymous | PPO, V290M, VP |
Gene |
UniProtKB-ID:
PPOX_HUMAN
UniprotKB:
P50336
UniParc:
UPI0000000C3C
EMBL:
U26446,
BC002357,
CH471121,
AL590714,
X99450,
D38537
Ensembl:
ENSG00000143224
KO:
hsa:5498
|
Nucleutide sequences |
EMBL-CDS:
BAA07538.1,
EAW52641.1,
AAA67690.1,
EAW52639.1,
EAW52636.1,
AAH02357.1
Ensembl_TRS:
ENST00000352210,
ENST00000367999
|
Protein sequencees |
Ensembl_PRO:
ENSP00000343943,
ENSP00000356978
RefSeq:
XP_011507965.1,
XP_016857060.1,
XP_006711469.2,
XP_011507981.1,
NP_001337057.1,
XP_016857051.1,
XP_011507970.1,
XP_011507972.1,
XP_006711465.2,
NP_001352329.1,
NP_001116236.1,
XP_011507969.1,
XP_016857048.1,
NP_001352328.1,
XP_016857052.1,
XP_011507980.1,
XP_011507968.1,
NP_001337060.1,
NP_001352327.1,
XP_005245352.2,
XP_011507967.1,
XP_016857059.1,
XP_024303633.1,
XP_006711466.2,
XP_016857053.1,
XP_011507975.1,
XP_024303635.1,
XP_024303634.1,
XP_011507973.1,
NP_000300.1,
XP_024303632.1,
NP_001337059.1,
XP_011507983.1,
XP_006711467.2,
NP_001352330.1,
XP_011507974.1,
XP_011507976.1,
NP_001337058.1,
XP_011507966.1,
XP_005245348.2,
XP_016857056.1,
XP_016857055.1,
XP_011507984.1
|
Others |
UniRef100:
UniRef100_P50336
UniRef90:
UniRef90_P50336
UniRef50:
UniRef50_P50336
UniGene:
Hs.517373
CCDS:
CCDS1221.1
|
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Refseq |
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