| Type | Description |
|---|---|
| Definition | tetratricopeptide repeat domain 12 |
| Date | Results | Publications |
|---|---|---|
| 2020-04-18 10:18:00 | TTC12 Loss-of-Function Mutations Cause Primary Ciliary Dyskinesia and Unveil Distinct Dynein Assembly Mechanisms in Motile Cilia Versus Flagella. | 31978331 |
| 2019-06-08 13:21:00 | Meta-analysis found that the minor G-allele of rs2236709, mapping TTC12, was associated with self-reported smoking and higher plasma cotinine levels. This risk allele was linked to an increased ventral-striatal blood-oxygen level-dependent response during reward anticipation and with higher DRD2 gene expression in the striatum, but not with TTC12 or ANKK gene expression. | 30104163 |
| 2013-05-04 11:43:00 | TTC12 SNP rs7130431 was associated with heroin dependence. | 23303482 |
| 2011-07-02 10:19:00 | TTC12-ANKK1-DRD2s seemed to influence smoking behavior mainly in adolescence, and its effect is partially mediated by personality characteristics promoting drug-seeking behavior. | 21168125 |
| 2010-06-30 22:07:00 | Observational study of gene-disease association. (HuGE Navigator) | 20133381 |
| Type | IDs |
|---|---|
| Synonymous | TPARM |
| Gene |
UniProtKB-ID:
TTC12_HUMAN,
Q53G14_HUMAN,
A8K8G6_HUMAN,
J3KR69_HUMAN
UniprotKB:
Q9H892,
Q53G14,
A8K8G6,
J3KR69
UniParc:
UPI0000EE39B4,
UPI000036FFF6,
UPI000013F914,
UPI000013F906
EMBL:
AP000880,
EF445041,
AP002840,
AK023921,
BC032355,
AK223117,
AK292331,
CH471065,
AK000542
Ensembl:
ENSG00000149292
KO:
hsa:54970
|
| Nucleutide sequences |
EMBL-CDS:
AAH32355.1,
BAB14725.1,
BAA91242.1,
BAD96837.1,
BAF85020.1,
EAW67214.1,
ACA06093.1,
EAW67213.1
Gene_ORFName:
hCG_2043014,
hCG_2043014
Ensembl_TRS:
ENST00000494714,
ENST00000314756,
ENST00000529221,
ENST00000483239
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000315160,
ENSP00000435291,
ENSP00000433757,
ENSP00000419652
RefSeq:
XP_016873434.1,
XP_016873432.1,
NP_001338966.1,
NP_001305462.1,
XP_016873439.1,
NP_060338.3,
NP_001364993.1,
XP_016873433.1,
XP_005271661.1,
XP_024304362.1,
XP_016873436.1,
NP_001364994.1,
XP_016873437.1,
NP_001364992.1,
XP_016873435.1,
XP_016873438.1,
XP_024304364.1,
XP_024304365.1
|
| Others |
UniRef100:
UniRef100_Q9H892,
UniRef100_Q53G14,
UniRef100_J3KR69
UniRef90:
UniRef90_Q9H892
UniRef50:
UniRef50_Q9H892
UniGene:
Hs.288772
CCDS:
CCDS8360.2
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员