| Type | Description |
|---|---|
| Definition | TIMELESS interacting protein |
| Date | Results | Publications |
|---|---|---|
| 2017-09-23 13:05:00 | the 1.85 A crystal structure of a large N-terminal segment of human Timeless, spanning amino acids 1-463, is presented and this region of human Timeless harbours a partial binding site for Tipin. | 28334766 |
| 2016-08-20 10:14:00 | TIPIN is important for the maintenance of DNA replication and represents a potential treatment target for the worst prognosis associated breast cancers, such as Triple-negative breast cancer. | 26004086 |
| 2013-07-13 13:16:00 | Tim-Tipin complex (or Tim alone) is able to associate with DNA polymerase epsilon bound to a 40-/80-mer DNA ligand. | 23511638 |
| 2013-04-13 10:29:00 | Tim-Tipin complex might play a role in coupling DNA unwinding and DNA synthesis by directly affecting the catalytic activities of replication fork proteins. | 23359676 |
| 2011-08-06 11:13:00 | We now show that cellular DNA replication fork pausing and protection factors Timeless (Tim) and Tipin (Timeless-interacting protein) accumulate at OriP during S phase of the cell cycle. | 21490103 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
TIPIN_HUMAN,
B4DRF3_HUMAN
UniprotKB:
Q9BVW5,
B4DRF3
UniParc:
UPI00017A7BDA,
UPI000013D21A
EMBL:
BK001386,
CH471082,
BC000870,
AK299233,
EU551725,
AK000523,
AC055855
Ensembl:
ENSG00000075131
KO:
hsa:54962
|
| Nucleutide sequences |
EMBL-CDS:
DAA01365.1,
BAA91229.1,
ACB21044.1,
EAW77762.1,
AAH00870.1,
BAG61265.1
Ensembl_TRS:
ENST00000261881
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000261881
RefSeq:
XP_024305741.1,
XP_005254579.1,
XP_011520045.1,
XP_024305740.1,
NP_001276915.1,
NP_060328.3,
XP_024305742.1,
XP_016877880.1,
XP_024305739.1,
XP_005254578.2,
XP_016877879.1,
XP_006720657.1
|
| Others |
UniRef100:
UniRef100_B4DRF3,
UniRef100_Q9BVW5
UniRef90:
UniRef90_Q9BVW5,
UniRef90_B4DRF3
UniRef50:
UniRef50_G1PBU4,
UniRef50_Q9BVW5
UniGene:
Hs.744308
CCDS:
CCDS10215.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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