| Type | Description |
|---|---|
| Definition | spermatogenesis and oogenesis specific basic helix-loop-helix 2 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-13 10:10:00 | Sohlh2 alleviates malignancy of EOC cells under hypoxia via inhibiting the HIF1alpha/CA9 signaling pathway. | 31318683 |
| 2019-11-09 12:52:00 | Data found that sohlh2 overexpression inhibited breast cancer cell proliferation in vitro and tumor growth in vivo. In contrast, sohlh2 silencing induced the opposite effects. These functional effects of sohlh2 were exerted through inhibiting Wnt/beta- catenin signaling by the increase of APC expression. These findings provide a novel mechanistic role of sohlh2 in breast tumorigenesis. | 30720232 |
| 2018-02-24 11:02:00 | sohlh2 functions as a tumor metastasis suppressor via suppressing IL-8 expression in breast cancer | 27384482 |
| 2017-07-29 10:51:00 | Results identified MMP9 as a novel target for transcriptional inactivation by Sohlh2 and demonstrated that the Sohlh2 downregulation of MMP9 is critical for inhibiting human ovarian cancer cell invasion. | 26153894 |
| 2016-05-28 11:12:00 | the expression of Sohlh genes in human tissues | 26375665 |
| Type | IDs |
|---|---|
| Synonymous | SOSF2, SPATA28, TEB1, bHLHe81 |
| Gene |
UniProtKB-ID:
SOLH2_HUMAN
UniprotKB:
Q9NX45
UniParc:
UPI00017A803A,
UPI000006D052,
UPI000007072A
EMBL:
AL160392,
AK301863,
AL139377,
BC025383,
CH471075,
AK000456,
AY884305
Ensembl:
ENSG00000120669
KO:
hsa:54937,
hsa:100526761
|
| Nucleutide sequences |
EMBL-CDS:
EAX08554.1,
EAX08555.1,
BAA91175.1,
BAG63302.1,
AAW78547.1,
AAH25383.1
Ensembl_TRS:
ENST00000379881,
ENST00000317764
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000326838,
ENSP00000369210
RefSeq:
NP_001269076.1,
NP_060296.2
|
| Others |
UniRef100:
UniRef100_Q9NX45
UniRef90:
UniRef90_Q9NX45
UniRef50:
UniRef50_Q9NX45
UniGene:
Hs.124519
CCDS:
CCDS61309.1,
CCDS9355.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员